Single-cell repertoire analysis demonstrates that clonal expansion is a prominent feature of the B cell response in multiple sclerosis cerebrospinal fluid

GP Owens, AM Ritchie, MP Burgoon… - The Journal of …, 2003 - journals.aai.org
… B cell repertoire of viral meningitis CSF was predominately polyclonal, whereas B cell clonal
expansion was a prominent feature … One clonal B cell population revealed multiple L chain …

[HTML][HTML] … apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell …

F Heller, A Fromm, AH Gitter, J Mankertz… - Mucosal …, 2008 - Elsevier
… a colonic epithelial cell culture model. For studying these epithelial features in response to
… end labeling (TUNEL) staining in HT-29/B6 cell monolayers. In contrast to interferon-γ, IL-13 …

[HTML][HTML] Expansion of atypical memory B cells is a prominent feature of COVID-19

B Oliviero, S Varchetta, D Mele, S Mantovani… - Cellular & molecular …, 2020 - nature.com
… A hallmark of COVID-19 is lymphopenia, involving virtually all cell lineages, … responses
in COVID-19. With respect to the latter, most studies focused on phenotypic and molecular T-cell

Intrathymic epstein‐barr virus infection is not a prominent feature of myasthenia gravis

K Kakalacheva, MA Maurer, B Tackenberg… - Annals of …, 2011 - Wiley Online Library
… EBV-specific T cells. The moderate elevation of CD8 + T-cell responses to MHC class I-…
Next, we assayed EBV and HCMV peptide-specific T-cell responses, enumerating IFNγ-positive …

Cellular stress responses: cell survival and cell death

S Fulda, AM Gorman, O Hori… - … journal of cell biology, 2010 - Wiley Online Library
… of stress a cell can encounter and the different responses that are … or contribution of
cellular stress responses to disease states. … Thus one of the prominent targets of this free-radical-…

Lack of prominent peptide–major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

SJ Turner, K Kedzierska, H Komodromou… - Nature …, 2005 - nature.com
response. Thus, the lack of prominent features in an antigenic complex of peptide and major
histocompatibility complex class I is associated with a diminished spectrum of TCR usage. …

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

S Monti, KJ Savage, JL Kutok, F Feuerhake, P Kurtin… - Blood, 2005 - ashpublications.org
… dendritic cells. The HR cluster shared features of histologically defined T-cell/histiocyte-rich
B-cell … microenvironment and host inflammatory response as defining features in DLBCL and …

The cell-type specific connectivity of the local cortical network explains prominent features of neuronal activity

TC Potjans, M Diesmann - arXiv preprint arXiv:1106.5678, 2011 - arxiv.org
… While the available connectivity maps have been used in various computational studies,
prominent features of the simulated activity such as the spontaneous firing rates do not match …

T cell responses: naive to memory and everything in between

ND Pennock, JT White, EW Cross… - Advances in …, 2013 - journals.physiology.org
response initiated within the secondary lymphoid organs (SLOs… will summarize the T cell
response broken down into three … prominent, although not necessarily less important, T cell

The microenvironment of germ cell tumors harbors a prominent antigen-driven humoral response

SN Willis, SS Mallozzi, SJ Rodig, KM Cronk… - The Journal of …, 2009 - journals.aai.org
… Somatic mutation was a prominent feature in all clones examined. The fraction of sequences
belonging to clones in the three seminoma specimens was 79% (specimen 12088), 31% (…