[HTML][HTML] Estrogen receptor beta: the promising biomarker and potential target in metastases

A Božović, V Mandušić, L Todorović… - International Journal of …, 2021 - mdpi.com
The discovery of the Estrogen Receptor Beta (ERβ) in 1996 opened new perspectives in the
diagnostics and therapy of different types of cancer. Here, we present a review of the …

[HTML][HTML] Putative biomarkers and targets of estrogen receptor negative human breast cancer

ZJ Sahab, YG Man, SW Byers, QXA Sang - International journal of …, 2011 - mdpi.com
estrogen receptor-related putative breast cancer biomarkers, including those of putative breast
cancer stem cells, a minor population of estrogen receptor … a few promising cytoskeleton …

A gene expression biomarker identifies chemical modulators of estrogen receptor α in an MCF-7 microarray compendium

J Rooney, N Ryan, J Liu, R Houtman… - Chemical research in …, 2021 - ACS Publications
… Many EDCs interact with and modulate the activity of the two estrogen receptors (ERα and
ERβ) which regulate the effects of estrogen hormones including estradiol (E2) on the growth, …

[HTML][HTML] Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness–a randomized neoadjuvant trial comparison …

M Madeira, A Mattar, ÂF Logullo, FA Soares… - BMC cancer, 2013 - Springer
… The role of estrogen receptor beta (ER-β) in breast cancer (BC) remains unclear. Some
studies have suggested that ER-β may oppose the actions of estrogen receptor alpha (ER-α), …

Estrogen receptor beta in breast cancer—diagnostic and therapeutic implications

J Hartman, A Ström, JÅ Gustafsson - Steroids, 2009 - Elsevier
… More than 10 years have passed since the discovery of the second estrogen receptor, estrogen
receptor β (… Therefore, targeting angiogenesis is a promising new therapy in oncology. …

ER-α36: a novel biomarker and potential therapeutic target in breast cancer

X Su, X Xu, G Li, B Lin, J Cao, L Teng - OncoTargets and therapy, 2014 - Taylor & Francis
… Citation1 These pleiotropic effects of estrogen are related to estrogen receptors (ERs) which
… Therefore, ER-α36 is a promising biomarker for tumor behavior and therapeutic response, …

Estrogen receptor-alpha as a predictive biomarker in endometrioid endometrial cancer

FJ Backes, CJ Walker, PJ Goodfellow, EM Hade… - Gynecologic …, 2016 - Elsevier
estrogen exposure is a well-known major risk factor for endometrial cancer. Recent data has
suggested that estrogen receptor … (EMT), could be a promising prognostic marker [7], [8], [9]. …

Estrogen-related receptor α and estrogen-related receptor γ associate with unfavorable and favorable biomarkers, respectively, in human breast cancer

EA Ariazi, GM Clark, JE Mertz - Cancer research, 2002 - AACR
… clinicopathological indicators and mRNA profiles of estrogen receptors (ERs) and ErbB …
3,B), indicating that the prognostic potential of ERRβ is not promising. However, ERβ mRNA …

Novel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer

FEB May - Cancer management and research, 2014 - Taylor & Francis
… The potency of the agents is low, but promising results have been … Estrogen receptor beta
is reported to be expressed more … Estrogen receptor alpha might be a biomarker that predicts …

Selective estrogen receptor degraders (SERDs): a promising strategy for estrogen receptor positive endocrine-resistant breast cancer

Y Lu, W Liu - Journal of medicinal chemistry, 2020 - ACS Publications
Estrogen receptor (ER) plays important roles in gene … Selective estrogen receptor modulators
(SERMs) and aromatase … Fulvestrant, the only approved selective estrogen receptor