Graft of a tissue-engineered neural scaffold serves as a promising strategy to restore myelination after rat spinal cord transection

BQ Lai, JM Wang, EA Ling, JL Wu… - Stem cells and …, 2014 - liebertpub.com
Remyelination remains a challenging issue in spinal cord injury (SCI). In the present study,
we cocultured Schwann cells (SCs) and neural stem cells (NSCs) with overexpression of …

Cell therapeutic strategies for spinal cord injury

P Zhou, J Guan, P Xu, J Zhao, C Zhang… - Advances in Wound …, 2019 - liebertpub.com
promising strategy is the study with primate models, because the species’ spinal cord is the
closest to the human spinal cordstrategies. The comprehensive treatment of injury of spinal …

Novel combination strategies to repair the injured mammalian spinal cord

MB Bunge - The journal of spinal cord medicine, 2008 - Taylor & Francis
… Because there has been substantial progress in testing promising strategies for spinal
cord repair, the question is what combination therapy will be most efficacious. An initial …

Concise review: bridging the gap: novel neuroregenerative and neuroprotective strategies in spinal cord injury

CS Ahuja, M Fehlings - Stem cells translational medicine, 2016 - academic.oup.com
… Finally, we summarize the key neuroregenerative strategies of the … Promising neuroprotective
strategies to mitigate the … blood-spinal cord barrier exposes the cord to inflammatory cells, …

Cellular transplantation strategies for spinal cord injury and translational neurobiology

PJ Reier - NeuroRx, 2004 - Elsevier
Basic science advances in spinal cord injury and regeneration research have led to a
variety of novel experimental therapeutics designed to promote functionally effective axonal …

Efficacy of Schwann cell transplantation for spinal cord repair is improved with combinatorial strategies

MB Bunge - The Journal of physiology, 2016 - Wiley Online Library
Promising strategies are now reaching human clinical trial status. At present, combination
strategies seem necessary. One component will be cell transplantation to fill the spinal cord

Transplantation of umbilical cord–derived mesenchymal stem cells as a novel strategy to protect the central nervous system: technical aspects, preclinical studies, and …

J Dalous, J Larghero, O Baud - Pediatric research, 2012 - nature.com
cord (hUC) is a rich source of stem and progenitor cells including mesenchymal stem cells
(MSCs) derived either from the cord or from cord … investigation of these promising cells in …

Motor recovery after chronic spinal cord transection in rats: a proof-of-concept study evaluating a combined strategy

A Ibarra, E Mendieta-Arbesú… - CNS & Neurological …, 2019 - ingentaconnect.com
… At the moment, effective therapeutic strategies for neurological recovery are nonexistent.
Nevertheless, some experimental treatments have shown promising effects. For instance, …

Neuroprotection and regeneration strategies for spinal cord repair

EC Tsai, CH Tator - Current pharmaceutical design, 2005 - ingentaconnect.com
… Indeed, several of these strategies have been so promising in … cord has not yet been achieved
despite the many strategies that … will lead to successful therapeutic strategies in humans. …

Transplantation strategies in spinal cord regeneration

H Nornes, A Björklund, U Stenevi - Neural transplants: development and …, 1984 - Springer
… axons terminated within 300 /Jm from the center of the transection, and none were observed
… a promising bridging strategy because of the apparent inability of the damaged spinal cord