Parthanatos and its associated components: promising therapeutic targets for cancer

Y Zhou, L Liu, S Tao, Y Yao, Y Wang, Q Wei… - Pharmacological …, 2021 - Elsevier
… the parthanatos cascade represent promising therapeutic targets for cancer therapy. In …
promise targeted therapy of parthanatos and its associated components holds for cancer therapy. …

Promising therapeutic targets for treatment of rheumatoid arthritis

J Huang, X Fu, X Chen, Z Li, Y Huang… - Frontiers in …, 2021 - frontiersin.org
… are potential and promising therapeutics for further research. Epigenetic Targets for Treatment
of … , JQ1, suggesting that this family of proteins may be promising therapeutic targets (191). …

The apelinergic system: a promising therapeutic target

I Falcão-Pires, R Ladeiras-Lopes… - … on therapeutic targets, 2010 - Taylor & Francis
… and the diseases that may benefit in the future from its modulation as a therapeutic target. …
in humans is necessary for the development of novel apelinergic-based therapeutic targets. …

Promising therapeutic targets in neuroblastoma

KK Matthay, RE George, AL Yu - Clinical cancer research, 2012 - AACR
… New approaches with targeted therapy may improve efficacy without increased toxicity. In
this review we evaluate 3 promising targeted therapies: (i) 131 I-metaiodobenzylguanidine (…

A comprehensive review on MAPK: a promising therapeutic target in cancer

C Braicu, M Buse, C Busuioc, R Drula, D Gulei… - Cancers, 2019 - mdpi.com
The mitogen-activated protein kinase (MAPK) pathway is an important bridge in the switch
from extracellular signals to intracellular responses. Alterations of signaling cascades are …

miRNA: a promising therapeutic target in cancer

A Menon, N Abd-Aziz, K Khalid, CL Poh… - International journal of …, 2022 - mdpi.com
… Patent Updates for miRNA in Cancer Therapy Various miRNAs appear to be promising
therapeutic targets from a scientific perspective [191]. As seen by the sharp rise in the number of …

The mitochondrial death pathway: a promising therapeutic target in diseases

S Gupta, GEN Kass, E Szegezdi… - Journal of cellular and …, 2009 - Wiley Online Library
… Despite the lack of evidence for PT as a mechanism of apoptotic death in general, it may be
an important therapeutic target for inducing PT-mediated cell death selectively in certain cell …

S1PR1 as a novel promising therapeutic target in cancer therapy

N Rostami, A Nikkhoo, A Ajjoolabady, G Azizi… - … diagnosis & therapy, 2019 - Springer
… can be considered as potential anti-tumor therapeutic targets, alone or in combination therapies.
… the potential use of S1P signaling modulators as therapeutic targets in cancer therapy. …

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

X Sui, R Chen, Z Wang, Z Huang, N Kong… - Cell death & …, 2013 - nature.com
… Thus, understanding the novel function of autophagy may allow us to develop a promising
therapeutic strategy to enhance the effects of chemotherapy and improve clinical outcomes in …

MiR-138: A promising therapeutic target for cancer

HH Sha, DD Wang, D Chen, SW Liu, Z Wang… - Tumor …, 2017 - journals.sagepub.com
MicroRNAs are small noncoding RNAs which regulate gene expressions at post-transcriptional
level by binding to the 3′-untranslated region of target messenger RNAs. Growing …