… In conclusion, BMI‑1 may represent a promising target for the prevention and therapy of … In
conclusion, BMI-1 may represent a promising target for the prevention and therapy of various …

Focal adhesion kinase (FAK) and steroid receptor coactivator (Src) are intracellular (nonreceptor)
tyrosine kinases that physically and functionally interact to promote a variety of cellular …

… to the identification of multiple rational therapeutic targets. Whilst these have provided new
… we can fully optimize and realize the promise of epigenetic therapies. The most prosaic of …

… cascade make the control of XIAP expression an exceptionally promising molecular target
for modulating apoptosis. Therapeutic benefits can be derived from both the suppression of …

… complex may serve as a promising and novel therapeutic target for clinical treatment in …
in autoimmune diseases, as well as their potential as therapeutic target for these diseases. …

Atherosclerosis, a chronic inflammatory disorder of the arteries, is responsible for most deaths
in westernized societies with numbers increasing at a marked rate in developing countries…

Current treatments for the parasitic disease leishmaniasis are unsatisfactory due to their
route of administration, toxicity and expense. Resistance is also developing to first-line …

Arginase is a key hydrolase in the urea cycle that hydrolyses L-arginine to urea and L-ornithine.
Increasing number of studies in recent years demonstrate that two mammalian arginase …

Hepatocellular carcinoma (HCC) is a common malignant tumor of which the occurrence and
development, the tumorigenicity of HCC is involving in multistep and multifactor interactions. …

… Based on the reported studies to date, MMP-12 suppression could emerge as a
promising therapeutic target for several CNS diseases that were discussed in this review. …