[HTML][HTML] The adenosinergic signaling: a complex but promising therapeutic target for Alzheimer's disease

L Cellai, K Carvalho, E Faivre, A Deleau… - Frontiers in …, 2018 - frontiersin.org
… The overall view on A 2A R as a therapeutic target thus looks promising. … development
of AD and constitutes a major therapeutic target that needs to be thoughtfully evaluated. …

Proteasome, a promising therapeutic target for multiple diseases beyond cancer

Y Cao, H Zhu, R He, L Kong, J Shao… - … and Therapy, 2020 - Taylor & Francis
Proteasome is vital for intracellular protein homeostasis as it eliminates misfolded and
damaged protein. Inhibition of proteasome has been validated as a powerful strategy for anti-…

Angiogenesis: a promising therapeutic target for ovarian cancer

A Bamias, S Pignata, E Pujade-Lauraine - Critical reviews in oncology …, 2012 - Elsevier
… Apart from VEGF other angiogenesis-related factors also represent promising therapeutic
targets in cancer therapy. Platelet-derived growth factor (PDGF) is essential to pericyte …

Phospholamban: a promising therapeutic target in heart failure?

AG Schmidt, I Edes, EG Kranias - Cardiovascular drugs and therapy, 2001 - Springer
… protein, phospholamban, as potential therapeutic targets. We summarize structural and genetic
… /SR Ca2+ ATPase interaction may be a promising therapeutic approach for heart failure. …

[HTML][HTML] Peripheral membrane proteins: promising therapeutic targets across domains of life

DM Boes, A Godoy-Hernandez, DGG McMillan - Membranes, 2021 - mdpi.com
Membrane proteins can be classified into two main categories—integral and peripheral
membrane proteins—depending on the nature of their membrane interaction. Peripheral …

[HTML][HTML] Midkine (MDK) growth factor: a key player in cancer progression and a promising therapeutic target

PS Filippou, GS Karagiannis, A Constantinidou - Oncogene, 2020 - nature.com
promising therapeutic targets in personalized medicine? Many challenges lie ahead before
our complete understanding on the MDK-related network, contributing to MDK-driven cancer …

MUC1 is a promising therapeutic target for prostate cancer therapy

Y Li, PJ Cozzi - Current cancer drug targets, 2007 - ingentaconnect.com
therapeutic approaches, many patients die of secondary disease (metastases). Mucins are
used as diagnostic markers as well as therapeutic targetstherapeutic targets for CaP therapy, …

ANGPTL3: a novel biomarker and promising therapeutic target

S Jiang, GH Qiu, N Zhu, ZY Hu, DF Liao… - Journal of drug …, 2019 - Taylor & Francis
Angiopoietin-like protein 3 (ANGPTL3) belongs to a multifunctional secreted protein that
mainly expresses in the liver, and is regulated by numerous post-translational modifications, …

FGFR4: A promising therapeutic target for breast cancer and other solid tumors

KM Levine, K Ding, L Chen, S Oesterreich - Pharmacology & therapeutics, 2020 - Elsevier
The fibroblast growth factor receptor (FGFR) signaling pathway has long been known to cancer
researchers because of its role in cell survival, proliferation, migration, and angiogenesis…

Caveolin-1: A promising therapeutic target for diverse diseases

S Gokani, LK Bhatt - Current Molecular Pharmacology, 2022 - ingentaconnect.com
… diseased states provides insights into how it can be explored as a novel therapeutic target.
… Table 1 summarizes the role of caveolin-1 as a therapeutic target in the treatment of various …