… advanced thyroid tumors. … promoter mutations. We also show that TERT expression is more
dependent on the MAPK signaling pathway in thyroid cells without TERT promoter mutations. …

… for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer now … promoter
mutations was recently reported to be associated with poor outcomes of clinical papillary thyroid …

… different thyroid cancer cells from different origins to evaluate TERT promoter mutations.
BCPAP cells originating from PTC presented the CC228229TT TERT promoter mutation (Fig. 1A…

… alone in FTC [30], similar to the coexistence of BRAF V600E mutation with TERT promoter
mutations that is associated with sharply increased aggressive clinicopathological behavior, …

… of thyroid cancer patients. Materials and Methods: In this study, we evaluate TERT promoter
mutation status in thyroid cancer … resected thyroid cancers with TERT promoter mutations (…

… The only marker that we found to be significantly hypermethylated in thyroid cancers compared
with benign thyroid tumors was RAR-β2. The cutoff we chose identified 22% of papillary …

… for TERT promoter mutations inhuman tumorigenesis. … promoter mutations in thyroid cancers;
these mutations are particularly prevalent in aggressive thyroid cancers and BRAF mutation…

… between the TERT promoter mutation and disease malignancy … of studies of TERT promoter
mutations in TC and underscore … Finally, the targeting of TERT promoter mutations and the …

… Therefore, the significance of TERT promoter mutations in … of BRAF and TERT promoter
mutations were analyzed in … and treatment of thyroid nodules and differentiated thyroid cancer (31…

… telomerase, and TERT promoter mutations are enriched in advanced thyroid cancer. In this
study, … biology of differentiated thyroid cancer harboring TERT promoter mutations in Taiwan. …