Effects of isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals

RI Westphalen, HC Hemmings - … Journal of the American Society of …, 2003 - pubs.asahq.org
… Given the lack of direct effects of isoflurane and propofol on transporter function observed
in this study, it is unlikely that the presynaptic effects of these anesthetics on glutamate release …

Characterization of Abuse Properties of the Anesthetic Propofol Using the Self-administration Paradigm in Rats

FB Wadji - 2013 - library-archives.canada.ca
effects of propofol’s anxiolytic properties on propofol self-administration . 98 4.1.4 Propofol
Propofol self-administration was maintained under a more demanding fixed ratio schedule ...…

K-Cl Cotransporter 2–mediated Cl Extrusion Determines Developmental Stage–dependent Impact of Propofol Anesthesia on Dendritic Spines

M Puskarjov, H Fiumelli, A Briner, T Bodogan… - …, 2017 - pubs.asahq.org
… Interestingly, this manipulation, however, enabled propofol anesthesia at PND 10 to
facilitate induction of spines with large diameter, while the number of filopodia-like spines was …

Activation of anterior thalamic reticular nucleus GABAergic neurons promotes arousal from propofol anesthesia in mice

Y Liu, B Chen, Y Cai, Y Han, Y Xia, N Li… - Acta Biochimica et …, 2021 - academic.oup.com
… the effect of TRN GABAergic neurons on propofol anesthesia… ’ (DREADDs) system to
selectively manipulate the TRN GABAergic … To test the effects of selective activation of the TRN …

Propofol is an allosteric agonist with multiple binding sites on concatemeric ternary GABAA receptors

DJ Shin, AL Germann, AD Johnson, SA Forman… - Molecular …, 2018 - ASPET
… In control manipulations, we altered basal activity by using drugs active at the GABA-binding
site or by mutations that increase constitutive activity, and found that the changes in EC 50 …

Susceptibility of transcranial electric motor-evoked potentials to varying targeted blood levels of dexmedetomidine during spine surgery

M Mahmoud, S Sadhasivam, S Salisbury… - The Journal of the …, 2010 - pubs.asahq.org
… injury during surgical manipulations rather than known anesthetic effects. Most commonly
… primary effect of interests: dexmedetomidine effect, propofol effect, and dexmedetomidine × …

[HTML][HTML] Dexmedetomidine compared with propofol for pediatric sedation during cerebral angiography

K Peng, J Li, F Ji, Z Li - Journal of Research in Medical Sciences …, 2014 - ncbi.nlm.nih.gov
… apportioned randomly and equally to receive either propofol or dexmedetomidine sedation.
Patients in the propofol group received an initial bolus of intravenous propofol (1 mg/kg) and …

Evaluation of new propofol aqueous solutions for intravenous anesthesia

A Trapani, V Laquintana, A Lopedota, M Franco… - International Journal of …, 2004 - Elsevier
The aim of this study was to evaluate the potential of using three new aqueous formulations
of propofol for intravenous (iv) anesthesia. The first formulation can be prepared by using …

Direct electrical stimulation of premotor areas: different effects on hand muscle activity during object manipulation

L Fornia, M Rossi, M Rabuffetti, A Leonetti… - Cerebral …, 2020 - academic.oup.com
… of hand muscles during object manipulation, although their respective role in … effect of direct
electrical stimulation (DES) of the premotor cortex on the execution of a hand manipulation

GABAergic neurons in the nucleus accumbens are involved in the general anesthesia effect of propofol

J Yan, BN Hang, LH Ma, JT Lin, Y Zhou, XH Jiao… - Molecular …, 2023 - Springer
… Here, through chemicalgenetic and optogenetic manipulation, coupled with EEG data and
behavioral assessments, we found that GABAergic neurons in NAc play a key role in different …