… The proprotein convertases represent a family of nine proteinases, … convertases in cholesterol
and lipid metabolism. Thus, PC5/6, PACE4 and Furin upregulate high-density lipoprotein (…

… in lipid, glucose, and bile acid (BA) metabolism, each of which can influence HDL metabolism…
We propose an integrative model in which PCSK members regulate HDL metabolism …

… as neural apoptosis regulated convertase 1 (NARC-1), is a member of the subtilisin-like
serine protease family that includes seven basic amino acid-specific proprotein convertases (PC)…

… Proprotein convertase subtilisin kexin type 9 (PCSK9) is the ninth member belonging to a
special family of proteases denoted as the proprotein convertases (PCs), including 8 other …

… lipid metabolism and to the initiation and progress of atherosclerosis and ischemic stroke. The
importance of PCSK9 has recently been recognized in lipid metabolism, … lipid metabolism. …

… , Pro-protein Convertase … Lipoprotein (LDL) receptor in the liver. Emerging data suggest
that PCSK9 might play a role in the modulation of triglyceride-rich lipoprotein (TGRL) metabolism…

… proprotein convertases (PCs), but not the atypical PCs S1P and PCSK9, decreases plasma
HDL-C levels. This metabolic … proteolytic events in lipid and lipoprotein metabolism as well. …

… at various levels with lipid metabolism; this leads to a derangement of the lipid profile and
to … role of proprotein convertase subtilisin/kexin type 9 (PCSK9) in lipoprotein metabolism. …

… secreted by the intestine and are responsible for transporting absorbed dietary lipids to …
state of postprandial lipid and lipoprotein metabolism. LPL (lipoprotein lipase) hydrolyzes …

… subtilisin/ kexin-like proprotein convertases (PCs) in rodents … , and/or modified lipid/sterol
metabolism. Members of the PC … amino acid-specific proprotein convertases, namely: PC1/3, …