Mechanisms underlying “functional” progesterone withdrawal at parturition

AG Brown, RS Leite… - Annals of the New York …, 2004 - Wiley Online Library
… ” progesterone withdrawal within fundal uterine smooth muscle cells. Pathological or normal
inflammation can promote the synthesis and secretion of prostaglandinsProstaglandins can …

Antiprogestins as a model for progesterone withdrawal

HOD Critchley, RW Kelly, RM Brenner, DT Baird - Steroids, 2003 - Elsevier
… Antagonism of progesterone action results in an inhibition of PGDH expression. Taken … in
response to progesterone withdrawal result in an elevation of prostaglandin concentrations (…

[引用][C] Progesterone withdrawal: effects on prostaglandins and parturition

MD Mitchell, APF Flint - Prostaglandins, 1977 - Elsevier
… therefore been impossible to separate these two potential stimuli for prostaglandin … of
progesterone withdrawal alone we have administered an inhibitor of the synthesis of progesterone

Progesterone withdrawal: key to parturition

T Zakar, F Hertelendy - American journal of obstetrics and gynecology, 2007 - Elsevier
… shortly before the onset of parturition is due to the death of the corpus luteum mediated
by prostaglandin F 2α (PGF 2α ). FP receptor knockout mice fail to deliver their pups at term …

Role of inflammatory mediators in human endometrium during progesterone withdrawal and early pregnancy

HOD Critchley, RL Jones, RG Lea… - The Journal of …, 1999 - academic.oup.com
PROGESTERONE (P 4 ) is essential for nurturing a successful pregnancy. The local tissue
response to withdrawal … inflammatory response, ie release of prostaglandins (PGs), increased …

[引用][C] Effects of progesterone withdrawal on uterine prostaglandin levels in the ovariectomized pregnant rat

PV Peplow - Prostaglandins, leukotrienes and essential fatty acids, 1991 - Elsevier
… + progesterone inserted on day 16, progesterone withdrawn … and 24 h after progesterone
or sham withdrawal and levels of … found at 24 h after progesterone withdrawal. Although not …

[HTML][HTML] Prostaglandin treatment is associated with a withdrawal of progesterone and androgen at the receptor level in the uterine cervix

Y Vladic-Stjernholm, T Vladic, CS Blesson… - Reproductive Biology …, 2009 - Springer
Prostaglandin-E 2 was reported to induce a functional progesterone withdrawal in vitro
by increasing the inhibitory PR-A over PR-B expression through the protein kinase (PK)-C …

[HTML][HTML] Progesterone receptor expression declines in the guinea pig uterus during functional progesterone withdrawal and in response to prostaglandins

TN Welsh, JJ Hirst, H Palliser, T Zakar - PLoS One, 2014 - journals.plos.org
… functional progesterone withdrawal occurs during late pregnancy and labor in vivo. We have
also … whether prostaglandins that induce labor cause functional progesterone withdrawal by …

Effect of progesterone withdrawal on hypothalamic mechanisms related to prolactin release in late pregnant rats

MM Bonafede, SR Valdez… - …, 2011 - karger.com
… Background/Aims: Progesterone (P 4) fall provoked by spontaneous or prostaglandin F2α
(PGF2α)-induced luteolysis in late pregnant rats triggers a prolactin (PRL) surge 12–24 h later. …

… of inhibition of prostaglandin synthesis on cervical softening and uterine activity during ovine parturition resulting from progesterone withdrawal induced by epostane

WL Ledger, MA Webster… - Journal of …, 1985 - joe.bioscientifica.com
… In the present study, epostane has been used to investigate the effects of progesterone
withdrawal on cervical softening in the pregnant ewe. Few attempts have been made to …