Androgen receptor in prostate cancer
CA Heinlein, C Chang - Endocrine reviews, 2004 - academic.oup.com
… 90% of prostate cancers are dependent on androgen at initial diagnosis, and endocrine
therapy of prostate cancer is directed toward the reduction of serum androgens and inhibition of …
therapy of prostate cancer is directed toward the reduction of serum androgens and inhibition of …
[HTML][HTML] Role of androgen receptor in prostate cancer: a review
K Fujita, N Nonomura - The world journal of men's health, 2019 - ncbi.nlm.nih.gov
… Androgen deprivation therapy can suppress hormone-naïve prostate cancer, but prostate
cancer changes AR and adapts to survive under castration levels of androgen. These …
cancer changes AR and adapts to survive under castration levels of androgen. These …
Androgen receptor signaling in prostate cancer
… downregulation of androgen levels in the circulation or blockade of the androgen receptor
(AR… and/or nonsteroidal anti-androgens hydroxyflutamide and bicalutamide are considered for …
(AR… and/or nonsteroidal anti-androgens hydroxyflutamide and bicalutamide are considered for …
Androgen receptor as a target in androgen-independent prostate cancer
SP Balk - Urology, 2002 - Elsevier
… survival after androgen ablation and to growth of androgen-independent prostate cancer. …
contribute to AR activity in androgen-independent prostate cancer, including AR amplification, …
contribute to AR activity in androgen-independent prostate cancer, including AR amplification, …
Androgen receptor: structure, role in prostate cancer and drug discovery
… Androgens and androgen receptors (AR) play a pivotal … as androgen insensitivity syndrome
(AIS) and prostate cancer, are associated with alterations in AR functions. Indeed, androgen …
(AIS) and prostate cancer, are associated with alterations in AR functions. Indeed, androgen …
Androgen receptors in prostate cancer.
… Gregory CW, Johnson RTJ, Mohler JL, French FS & Wilson EM 2001b Androgen receptor
stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. …
stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. …
Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer
ME Taplin, GJ Bubley, TD Shuster… - … England Journal of …, 1995 - Mass Medical Soc
… -independent prostate cancer. In this report we show that in 5 of 10 patients with metastatic
androgen-independent prostate cancer, the androgen-receptor genes had point mutations, …
androgen-independent prostate cancer, the androgen-receptor genes had point mutations, …
The role of androgens and the androgen receptor in prostate cancer
JD Debes, DJ Tindall - Cancer letters, 2002 - Elsevier
… Prostate cancer (PCa) is the leading diagnosed malignancy in men in … androgens and
the androgen receptor (AR) has been studied extensively in PCa. Plasma levels of androgens …
the androgen receptor (AR) has been studied extensively in PCa. Plasma levels of androgens …
Androgen receptor mutations in prostate cancer
M Marcelli, M Ittmann, S Mariani, R Sutherland… - Cancer research, 2000 - AACR
… We analyzed the frequency and relevance of mutations in the coding region of the androgen
receptor (AR) in genomic DNA extracted from 137 specimens of prostate cancer. The …
receptor (AR) in genomic DNA extracted from 137 specimens of prostate cancer. The …
Androgen receptor structural and functional elements: role and regulation in prostate cancer
SM Dehm, DJ Tindall - Molecular endocrinology, 2007 - academic.oup.com
… prostatic hyperplasia and prostate cancer (PCa). Androgen action is exerted through the
androgen receptor (AR), a 110-kDa member of the steroid receptor family of transcription factors…
androgen receptor (AR), a 110-kDa member of the steroid receptor family of transcription factors…
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