Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

PJ Kaplan‐Lefko, TM Chen, MM Ittmann… - … Prostate, 2003 - Wiley Online Library
models for human cancer, it becomes very important that we describe each mouse model as
… anatomical features of the murine prostate differ from the human prostate. Moreover, unlike …

Pathologic progression of autochthonous prostate cancer in the TRAMP model

JR Gingrich, RJ Barrios, BA Foster… - … cancer and prostatic …, 1999 - nature.com
… of one autochthonous transgenic animal model of prostate cancer, … of Mouse Prostate (TRAMP).
The general features of the TRAMP model and other transgenic prostate cancer models

[HTML][HTML] A Western-type diet accelerates tumor progression in an autochthonous mouse model of prostate cancer

G Llaverias, C Danilo, Y Wang, AK Witkiewicz… - The American journal of …, 2010 - Elsevier
… TRAMP mouse model. As a result, our studies clarify and validate the role of a Western-type
diet previously examined in xenograft models during the development of prostate cancer. …

Autochthonous mouse models for prostate cancer: past, present and future

WJ Huss, LA Maddison, NM Greenberg - Seminars in cancer biology, 2001 - Elsevier
… To this end mouse models have an essential role in prostate cancer … of autochthonous
murine models of prostate cancer, the essentials of the idealized mouse model for prostate cancer

Differentially expressed genes and molecular pathways in an autochthonous mouse prostate cancer model

S Verma, S Shukla, M Pandey, GT MacLennan… - Frontiers in …, 2019 - frontiersin.org
… To date, numerous mouse models are developed that have advanced the area of prostate
cancer research. Some established animal models include tumor suppressor knockout PTEN …

DNA methylation pathway alterations in an autochthonous murine model of prostate cancer

SR Morey, DJ Smiraglia, SR James, J Yu, MT Moser… - Cancer research, 2006 - AACR
autochthonous murine prostate cancer model, transgenic adenocarcinoma of mouse prostate
(… reminiscent of human prostate cancer, supporting the use of this model to investigate the …

… tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice

TM Williams, GS Hassan, J Li, AW Cohen… - Journal of Biological …, 2005 - ASBMB
prostate cancer-derived cell lines. Here, we employed a well established transgenic mouse
model of prostate cancer… role of Cav-1 in modulating prostate carcinogenesis in vivo. For this …

Mouse models of prostate cancer: picking the best model for the question

MM Grabowska, DJ DeGraff, X Yu, RJ Jin… - Cancer and Metastasis …, 2014 - Springer
… Consortium initiated the Prostate Steering Committee 15 years ago, there … mouse (GEM)
models of prostate cancer (PCa). Today, a PubMed search for “prostate cancer mouse model” …

Constitutive activation of PI3K‐Akt and NF‐κB during prostate cancer progression in autochthonous transgenic mouse model

S Shukla, GT MacLennan, SR Marengo… - … Prostate, 2005 - Wiley Online Library
… of the mouse prostate (TRAMP) has emerged as an excellent mouse model of prostate
cancer [31]. TRAMP males spontaneously develop prostatic adenocarcinoma that progresses …

Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer

N Polnaszek, B Kwabi-Addo, LE Peterson, M Ozen… - Cancer research, 2003 - AACR
… , we used the TRAMP model of prostate cancer, an autochthonous transgenic model of
prostate cancer that has been used by many groups. TRAMP mice were originally generated by …