… susceptibility genes in prostate cancer risk. Although a number of rare highly penetrant loci
contribute to the Mendelian inheritance of prostate cancer, … a susceptibility to prostate cancer …

… dependency of human prostate cancer, we are developing a polygenic model of prostate
cancer susceptibility. We describe below the rationale on which this prostate cancer model is …

… of these susceptibility genes in prostate cancer risk. It is … prostate cancer harbor germline
mutation in the BRCA2 gene thus confirming its role as a high-risk prostate cancer susceptibility …

… prostate cancer chromatin immunoprecipitation and sequencing experiments with genotype
and gene expression data from 602 prostate … target genes in prostate cancer cell line models…

… prostate cancer susceptibility loci associated with aggressive and non-aggressive disease.
… A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility …

… cell line, but not other prostate cancer cell lines. To understand the mechanism of galectin-1
sensitivity of LNCaP cells compared with other prostate cancer cells, we … in these cells, and …

… of prostate cancer, we compared the prevalence of the 657del5 NBS1 founder allele in 56
patients with familial prostate cancer, 305 patients with nonfamilial prostate cancer, … prostate …

… IAP knockdown could sensitise prostate cancer cells to apoptosis, and … cell death, the impact
of specific inhibition of single or multiple IAPs on long term survival of prostate cancer cells …

… It is now well-documented that androgens play a key role in prostate carcinogenesis. We
have proposed a multigenic model for prostate cancer susceptibility, featuring genes involved …

… prostate cancer biology (eg, AR) that are not detected by eQTL-based methods. HiChIP
predicted enhancer elements at the AR and NKX3-1 prostate cancer … in LNCaP cells. Our results …