Up-regulation of TWIST in prostate cancer and its implication as a therapeutic target

WK Kwok, MT Ling, TW Lee, TCM Lau, C Zhou… - Cancer research, 2005 - AACR
… In this study, we found up-regulation of TWIST in human prostate cancer and increased …
Inactivation of TWIST in androgen-independent prostate cancer cells resulted in increased …

Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells

G Pandini, R Mineo, F Frasca, CT Roberts Jr… - Cancer research, 2005 - AACR
regulation of the IGF system in prostate cancer are lacking. We studied whether in human
AR-positive prostate cancer cells … induce a selective and marked up-regulation of the IGF-IR. …

[HTML][HTML] Up-regulated microRNA-143 in cancer stem cells differentiation promotes prostate cancer cells metastasis by modulating FNDC3B expression

X Fan, X Chen, W Deng, G Zhong, Q Cai, T Lin - BMC cancer, 2013 - Springer
… PC-3 sphere cells and progressively increased during sphere re-adherent culture. Moreover,
the down-regulation of miR-143 suppressed prostate cancer cells migration and invasion …

Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer

K Halkidou, L Gaughan, S Cook, HY Leung… - … Prostate, 2004 - Wiley Online Library
… Moreover, we show that HDAC1’s upregulation in CaP can be partly caused by androgen
ablation. Surgical or hormonal castration is the sole effective therapy for advanced disease …

Signal pathways in up-regulation of chemokines by tyrosine kinase MER/NYK in prostate cancer cells

YM Wu, DR Robinson, HJ Kung - Cancer research, 2004 - AACR
… of kinases, in the up-regulation of chemokines in prostate cancer cells. We show that NYK …
of tumor specimens and prostate cancer cell lines. Activation of NYK in the prostate cancer cell

[HTML][HTML] KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3

X Huang, X Li, B Guo - Journal of biological chemistry, 2008 - ASBMB
cancer. KLF6 suppresses tumor growth and induces apoptosis in cancer cells through …
Here we show that KLF6 induces apoptosis in prostate cancer cells by ATF3 (activating …

Genistein‐induced upregulation of p21 WAF1 , downregulation of cyclin B, and induction of apoptosis in prostate cancer cells

JN Davis, B Singh, M Bhuiyan, FH Sarkar - 1998 - Taylor & Francis
Upregulation of p2\mF1 protein expression in LNCaP (left) and PC3 (right) prostate cancer
cell lines treated with genistein. Cultures at 70% confluency were treated with 0, 30, and 50 …

Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy

X Liu, JC Cheng, LS Turner, S Elojeimy… - Expert opinion on …, 2009 - Taylor & Francis
cell growth. The mechanism for this transition remains unclear. However it is currently the
leading problem in prostate cancer treatment… -dependent LNCaP prostate cancer cells followed …

Platelet‐derived microparticles promote invasiveness of prostate cancer cells via upregulation of MMP‐2 production

O Dashevsky, D Varon, A Brill - International journal of cancer, 2009 - Wiley Online Library
… The impact of platelets in prostate cancer metastasis has been suggested.14 However, the
exact … We herein demonstrate that PMPs promote prostate cancer cell invasion in vitro by …

Pharmacological upregulation of prostate‐specific membrane antigen (PSMA) expression in prostate cancer cells

B Kranzbühler, S Salemi, CA Umbricht, C Müller… - … Prostate, 2018 - Wiley Online Library
… Here, we demonstrate that different compounds can increase the expression of PSMA in
LNCaP prostate cancer cells. Additionally, we show for the first time that dutasteride and …