[HTML][HTML] Mechanisms of resistance in castration-resistant prostate cancer (CRPC)

T Chandrasekar, JC Yang, AC Gao… - … andrology and urology, 2015 - ncbi.nlm.nih.gov
… axis in the development of CRPC lies in the … CRPC compared to hormone-naïve prostate
cancer (18-21). Recent studies have demonstrated that intra-tumoral androgen levels in CRPC

Characterising the castration‐resistant prostate cancer population: a systematic review

M Kirby, C Hirst, ED Crawford - International journal of clinical …, 2011 - Wiley Online Library
… Our study identified five papers that evaluated the prevalence of CRPC in patients with
prostate cancer. Estimates of the proportion of prostate cancer patients who develop CRPC

Advances in prostate cancer treatment

D Trewartha, K Carter - Nature reviews. Drug discovery, 2013 - nature.com
… The historic standard treatment for metastatic castration-resistant prostate cancer (CRPC),
docetaxel, provides a median overall survival improvement of roughly 3 months. …

[HTML][HTML] Role of androgen receptor in prostate cancer: a review

K Fujita, N Nonomura - The world journal of men's health, 2019 - synapse.koreamed.org
… in prostate cancer and the development of CRPC and promising new agents against CRPC.
… In the progression of prostate cancer to CRPC, prostate cancer survives and resumes its …

[HTML][HTML] Guidelines for the management of castrate-resistant prostate cancer

F Saad, SJ Hotte - Canadian Urological Association Journal, 2010 - ncbi.nlm.nih.gov
… the terms CRPC or castration recurrent prostate cancer were … in the resistant of prostate
cancer cells to testosterone … the Prostate Cancer Working Group (PCWG2) defined CRPC

Who dies from prostate cancer?

A Patrikidou, Y Loriot, JC Eymard, L Albiges… - … cancer and prostatic …, 2014 - nature.com
… We used two monthly curated databases of patients with castration-resistant prostate
cancer (CRPC) to describe the natural history of patients dying of CaP in the modern era. …

The Prostate Cancer Working Group 3 (PCWG3) consensus for trials in castration-resistant prostate cancer (CRPC).

HI Scher, MJ Morris, WM Stadler, CS Higano, S Halabi… - 2015 - ascopubs.org
… Background: The availability of new agents for men with CRPC, recognition of new disease
phenotypes, and an evolving regulatory environment have created the need for new CRPC

[HTML][HTML] Circulating tumour cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): a single-centre experience

D Olmos, HT Arkenau, JE Ang, I Ledaki, G Attard… - Annals of oncology, 2009 - Elsevier
… -resistant prostate cancer (CRPC) is a heterogeneous disease with prognoses varying
significantly between patients. In addition, the assessment of treatment response in CRPC

New therapies for castration-resistant prostate cancer: efficacy and safety

H Beltran, TM Beer, MA Carducci, J De Bono… - European urology, 2011 - Elsevier
… The average survival for patients with castration-resistant prostate cancer (CRPC) is 2–3 yr.
… have enhanced our understanding of the biology of CRPC. Biomarkers are considered in the …

Molecular and cellular mechanisms of castration resistant prostate cancer

Y Huang, X Jiang, X Liang, G Jiang - Oncology letters, 2018 - spandidos-publications.com
… With increases in the mortality rate and number of patients with prostate cancer (PCa), PCa,
… resistant prostate cancer (CRPC), which eventually led to mortality. Due to CRPC being …