… DNA methylation by M-NGS in prostate cells To perform a genome-wide analysis of DNA
methylation in prostate cancer, … , which enriches methylated DNA using restriction enzymes and …

… of promoter regions leads to gene silencing in many cancers. In this study, we assessed
the effect of DNA methylation on the identification of recurrent prostate cancer. METHODS: We …

… This, perhaps, suggests that CpG methylation events in cancer … Within the prostate cancer
TCGA cohort, we examined the … control DNA methylation, known targets of DNA methylation …

… Methylation signatures specific to an individual’s cancer. We were next interested in plasma
DNA methylation changes that could potentially identify distinct methylation subtypes. The …

… methylation may be an important mechanism in prostate carcinogenesis. To screen for
epigenetically silenced miRNAs in prostate cancer (PCa), we treated prostate … the methylation …

… by DNA methylation has been noted in prostate cancer (45, 49). The frequencies of methylation
in CCND2 were significantly higher in prostate … between the methylation in CCND2 and …

… DNA methylation and prostate cancer DNA methylation plays an important role in DNA repair,
… DNA methylation involves the addition of a methyl group to the 5′-carbon of cytosine in …

… In this study, DNA damage, repair and DNA methylation changes … in prostate cancer cell
lines with varying sensitivities to DNA damage. Our analysis demonstrates that DNA methylation …

… cancer and created DNA methylation “cityscape” plots to visualize these complex data. We
show that somatic DNA methylation … with lethal metastatic prostate cancer, were maintained …

… 12 pairs of matched benign and prostate cancer tissue DNA from patients with prostate …
factors (NKX2-5) which we have identified to be differentially methylated in prostate cancer. …