MicroRNA-145 is regulated by DNA methylation and p53 gene mutation in prostate cancer

SO Suh, Y Chen, MS Zaman, H Hirata… - …, 2011 - academic.oup.com
… -145 is methylated at the promoter region in both prostate cancer tissues and 50 different types
of … of miR-145 is through DNA methylation and p53 mutation pathways in prostate cancer. …

Genetic factors regulating inflammation and DNA methylation associated with prostate cancer

M Ianni, E Porcellini, I Carbone, M Potenzoni… - … Cancer and Prostatic …, 2013 - nature.com
Background: Prostate cancer (PCa) displays a strong familiarity component and genetic
factors; genes regulating inflammation may have a pivotal role in the disease. Epigenetic …

[HTML][HTML] DNA methylation-guided prediction of clinical failure in high-risk prostate cancer

K Litovkin, A Van Eynde, S Joniau, E Lerut, A Laenen… - PLoS …, 2015 - journals.plos.org
Prostate cancer (PCa) is a very heterogeneous disease with respect to clinical outcome. This
study explored differential DNA methylation in a … DNA methylation, which occurs mainly on …

Epigenomic profiling of DNA methylation in paired prostate cancer versus adjacent benign tissue

MS Geybels, S Zhao, CJ Wong, M Bibikova… - … Prostate, 2015 - Wiley Online Library
… The goal of the present study was to evaluate DNA methylation profiles in paired PCa and
adjacent benign tissue samples. We aimed to find novel differentially methylated CpGs and …

[HTML][HTML] Recent advances in understanding DNA methylation of prostate cancer

HJ Shin, JT Hua, H Li - Frontiers in Oncology, 2023 - frontiersin.org
… used for evaluating DNA methylation changes and … DNA methylation as prostate cancer
biomarkers and its potential for developing targeted treatment of CIMP subtype of prostate cancer

[HTML][HTML] DNA methylation profiles in African American prostate cancer patients in relation to disease progression

R Rubicz, S Zhao, M Geybels, JL Wright, S Kolb… - Genomics, 2019 - Elsevier
… This study examined whether differential DNA methylation is associated with … and prostate
cancer recurrence in African American men, who are more likely to die from prostate cancer

Prostate tumor DNA methylation is associated with cigarette smoking and adverse prostate cancer outcomes

IM Shui, CJ Wong, S Zhao, S Kolb, EM Ebot… - Cancer, 2016 - Wiley Online Library
DNA methylation has been hypothesized as a … prostate cancer (PCa) outcomes. This study
was aimed at assessing whether smoking is associated with prostate tumor DNA methylation

[HTML][HTML] An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk

L Wu, Y Yang, X Guo, XO Shu, Q Cai, X Shu… - Nature …, 2020 - nature.com
… the identification of promising DNA methylation markers using a … Aligned with the recognized
role of DNA methylation in … target genes through influencing DNA methylation levels. In this …

[PDF][PDF] Abnormal DNA methylation, epigenetics, and prostate cancer

WG Nelson, S Yegnasubramanian, AT Agoston… - Front …, 2007 - article.imrpress.com
… So far, the use of assays for somatic alterations in DNA methylation in prostate cancer cells
as tools for prostate cancer detection, diagnosis, and prognosis has been largely restricted to …

Selenite reactivates silenced genes by modifying DNA methylation and histones in prostate cancer cells

N Xiang, R Zhao, G Song, W Zhong - Carcinogenesis, 2008 - academic.oup.com
… Accumulating data suggest that dietary factors may alter cancer risk by modifications of … to
regulate methylation-silenced genes in human prostate cancer cells. DNA methylation, histone …