… AR alterations enriched in mCRPC compared to primary prostate cancer. We identified …
mCRPC. We found no genes selectively mutated in primary prostate cancer compared to mCRPC…

… prostate cancer (mCRPC) … mCRPC and mutations in DNA damage repair genes has added
to the treatment armamentarium and improved personalized treatments for prostate cancer. …

… Prostate cancer (PCa) is one of the most common cancers in men. In the year 2020, an …
-resistant prostate cancer (mCRPC). The long-term prognosis for patients with mCRPC is poor, …

… In a phase I study [41] of men with mCRPC, it was shown to have an excellent … Prostate
Cancer Working Group in 2013 at the GU cancer symposium [42]. Among 46 men with mCRPC, …

… the management of advanced prostate cancer provides a range of treatment options with
notable benefits for men with metastatic castration-resistant prostate cancer (mCRPC). At the …

… /kg of avelumab in pts with mCRPC who had progressive disease (… Prostate cancer working
group 2 criteria were used to … on a population of pts with mCRPC. Immune analysis is under …

… of metastatic castration-resistant prostate cancer (mCRPC), increasing options available to
… of men with mCRPC. Toward this effort, recent studies evaluated mCRPC treatment patterns …

… Until recently, the only approved agent for metastatic castration-resistant prostate cancer (mCRPC)
was docetaxel chemotherapy. But over the last 5 years, significant advances in the …

… DDR = defective DNA repair; FPKM = Fragments Per Kilobase of transcript per Million
mapped reads; mCRPC = metastatic castration-resistant prostate cancer; PSMA = …

… is that the study population involved patients with mCRPC enrolled on clinical trials, which
may not be truly representative of all patients with prostate cancer. In fact, it is understood that …