AR splice variant 7 (AR-V7) and response to taxanes in men with metastatic castration-resistant prostate cancer (mCRPC).

ES Antonarakis, C Lu, Y Chen, B Luber, H Wang… - 2015 - ascopubs.org
… (CTCs) in men with mCRPC was associated with primary … prospectively enrolled patients
with mCRPC starting docetaxel or … AR-V7 in CTCs from men with mCRPC is not associated with …

Assessment of the bone scan index in a randomized placebo-controlled trial of tasquinimod in men with metastatic castration-resistant prostate cancer (mCRPC)

AJ Armstrong, R Kaboteh, MA Carducci… - … Oncology: Seminars and …, 2014 - Elsevier
Introduction Drug development and clinical decision making for patients with metastatic
prostate cancer (PC) have been hindered by a lack of quantitative methods of assessing …

Patient experience in the treatment of metastatic castration-resistant prostate cancer: state of the science

N Nussbaum, DJ George, AP Abernethy… - … cancer and prostatic …, 2016 - nature.com
… This end of the disease continuum is termed metastatic castration-resistant prostate cancer
(mCRPC), defined by cancer progression despite a testosterone level of <50 ng dl −1 (<1.7 …

Abiraterone and olaparib for metastatic castration-resistant prostate cancer

NW Clarke, AJ Armstrong, A Thiery-Vuillemin… - NEJM …, 2022 - evidence.nejm.org
… diphosphate[ADP]-ribose) polymerase inhibitor olaparib is combined with next-generation
hormonal agent abiraterone to treat metastatic castration-resistant prostate cancer (mCRPC). …

TheraP: 177Lu-PSMA-617 (LuPSMA) versus cabazitaxel in metastatic castration-resistant prostate cancer (mCRPC) progressing after docetaxel—Overall survival …

, … and New Zealand Urogenital and Prostate Cancer … - 2022 - ascopubs.org
5000 Background: We previously reported that in men with mCRPC progressing after
docetaxel randomly assigned LuPSMA vs. cabazitaxel (Lancet 2021), those assigned LuPSMA …

Docetaxel in the treatment of metastatic castration-resistant prostate cancer (mCRPC): an observational study in a single institution

D Schallier, L Decoster, J Braeckman… - Anticancer …, 2012 - ar.iiarjournals.org
Prostate cancer is the second most common cause of cancer … In patients with metastatic
prostate cancer, androgen … metastatic castration-resistant prostate cancer (mCRPC) leading to …

Progress in the treatment of advanced prostate cancer

CN Sternberg, DP Petrylak, RA Madan… - American Society of …, 2014 - ascopubs.org
… castration-resistant prostate cancer (mCRPC). There is now irrefutable evidence that the
AR axis is functional in most patients throughout the history of prostate cancer, is crucial from …

Enzalutamide (ENZA) in combination with abiraterone acetate (AA) in bone metastatic castration resistant prostate cancer (mCRPC).

E Efstathiou, MA Titus, S Wen, A SanMiguel, A Hoang… - 2014 - ascopubs.org
… (AR) and paracrine androgen biosynthesis in mCRPC may be more effective than either …
with AA in mCRPC Methods: We enrolled patients (pts) with progressive bone mCRPC, castrate …

Enzalutamide for the treatment of prostate cancer

SK Pal, CA Stein, O Sartor - Expert opinion on pharmacotherapy, 2013 - Taylor & Francis
… castration-resistant prostate cancer (mCRPC) in 2005 … among a growing list of agents for
mCRPC. A MEDLINE search was … of biomarkers to guide therapy for mCRPC is ideal, there are …

Overall survival and second primary malignancies in men with metastatic prostate cancer

J Mehtälä, J Zong, Z Vassilev, G Brobert, MS Gabarró… - PloS one, 2020 - journals.plos.org
… First, men diagnosed with bone metastatic PC (mPC cohort), and second, a subset of
men with mPC fulfilling conditions for castration resistant prostate cancer (mCRPC cohort). …