[HTML][HTML] Obesity and cancer: mechanistic insights from transdisciplinary studies

EH Allott, SD Hursting - Endocrine-related cancer, 2015 - erc.bioscientifica.com
… 2014), supporting a true biologic association between NSAID use and prostate cancer. Finally…
in the TRAMP mouse model of prostate cancer support a role for COX inhibition in prostate

Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: a mechanistic model supporting prevention strategies

H Lin, JP Lu, P Laflamme, S Qiao… - International …, 2010 - spandidos-publications.com
… a key role in the initiation and progression of prostate cancer (PC). We previously reported …
with prostate cell proliferation and mutagenesis. These results therefore support the rationale …

[HTML][HTML] Mechanistic targets for BPH and prostate cancer–a review

A Shah, AA Shah, NK, R Lobo - Reviews on Environmental Health, 2021 - degruyter.com
… All men, almost, suffer from prostatic disorders in average life expectancy. In the … of prostate
gland discovered the link between Benign prostatic hyperplasia (BPH) and Prostate Cancer (…

[HTML][HTML] Mechanistic support for combined MET and AR blockade in castration-resistant prostate cancer

Y Qiao, FY Feng, Y Wang, X Cao, S Han… - Neoplasia, 2016 - Elsevier
… the emergence of castration-resistant prostate cancer (CRPC). … to MET inhibition in prostate
cancer. Herein we show in … nearly exclusively in AR − prostate cancer. Importantly, AR …

The molecular evolution of castration-resistant prostate cancer

Y Ceder, A Bjartell, Z Culig, MA Rubin, S Tomlins… - European urology …, 2016 - Elsevier
… to persistent AR signalling as a major mechanism of progression to CRPC. Resistance due
… as a mechanism of resistance. The diversity of potential resistance mechanisms supports the …

Physical activity and its mechanistic effects on prostate cancer

A Wekesa, M Harrison, RW Watson - Prostate cancer and prostatic …, 2015 - nature.com
… In the meantime, to ensure continued support, we are … mechanism associating physical
activity with prostate cancer risk… components or the stage at prostate cancer diagnosis and (2) …

Epigenetics in prostate cancer: biologic and clinical relevance

C Jerónimo, PJ Bastian, A Bjartell, GM Carbone… - European urology, 2011 - Elsevier
… Reports were selected based on the detail of analysis, mechanistic support of data, novelty,
… publications on prostate cancer (PCa) epigenetics using the keywords prostate cancer, DNA …

Mechanisms underlying the development of androgen-independent prostate cancer

KJ Pienta, D Bradley - Clinical cancer research, 2006 - AACR
support of this mechanism includes (a) ethnic groups with higher levels of 5α-reductase activity
have a higher rate of prostate cancer … of dihydrotestosterone in prostatic tissue is reduced …

[HTML][HTML] Regulation of the pentose phosphate pathway by an androgen receptor–mTOR-mediated mechanism and its role in prostate cancer cell growth

E Tsouko, AS Khan, MA White, JJ Han, Y Shi… - Oncogenesis, 2014 - nature.com
… Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate
cancer: a mechanistic model supporting prevention strategies. Int J Oncol 2010; 37: 761–766. …

Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment

KS Koeneman, F Yeung, LWK Chung - The Prostate, 1999 - Wiley Online Library
… for prostate cancer to metastasize to bone has been explained by a number of theories.
The mechanical (or hemodynamic) mechanism of retrograde flow of prostate cancer cells …