[HTML][HTML] Prostate-specific membrane antigen heterogeneity and DNA repair defects in prostate cancer
A Paschalis, B Sheehan, R Riisnaes, DN Rodrigues… - European urology, 2019 - Elsevier
… of prostate cancer samples, we report that the presence of prostate-specific membrane antigen
(… We show for the first time that prostate cancers with defective DNA repair produce more …
(… We show for the first time that prostate cancers with defective DNA repair produce more …
Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer
… -tumoral heterogeneity perspective, we examined the degree of PSMA heterogeneity within
… This observed intra-tumoral heterogeneity of PSMA expression within liver metastases with …
… This observed intra-tumoral heterogeneity of PSMA expression within liver metastases with …
Heterogeneity of prostate-specific membrane antigen (PSMA) expression in prostate carcinoma with distant metastasis
S Mannweiler, P Amersdorfer, S Trajanoski… - Pathology & Oncology …, 2009 - Springer
… Overexpression of PSMA in the cell membrane of prostate cancer cells provides an
optimal target for therapy and diagnosis. In vivo radioscintigraphic imaging using PSMA …
optimal target for therapy and diagnosis. In vivo radioscintigraphic imaging using PSMA …
Prostate-Specific Membrane Antigen–Targeted Therapies for Prostate Cancer: Towards Improving Therapeutic Outcomes
… , both between different prostate cancer patients and within the same prostate tumor, …
assessing the heterogeneity of PSMA expression through IHC in primary prostate cancers revealed …
assessing the heterogeneity of PSMA expression through IHC in primary prostate cancers revealed …
Heterogeneous flare in prostate-specific membrane antigen positron emission tomography tracer uptake with initiation of androgen pathway blockade in metastatic …
R Aggarwal, X Wei, W Kim, EJ Small, CJ Ryan… - European Urology …, 2018 - Elsevier
… prostate-specific membrane antigen (PSMA) tracer uptake on positron emission tomography
scans are variably observed following initiation of hormone therapy for prostate cancer and …
scans are variably observed following initiation of hormone therapy for prostate cancer and …
[HTML][HTML] Prostate-specific membrane antigen biology in lethal prostate cancer and its therapeutic implications
B Sheehan, C Guo, A Neeb, A Paschalis… - European urology …, 2022 - Elsevier
… biopsy tissue from metastatic castration-resistant prostate cancer (mCRPC), which has higher
AR signalling [18], [19]. The heterogeneity in PSMA expression in advanced mCRPC may …
AR signalling [18], [19]. The heterogeneity in PSMA expression in advanced mCRPC may …
Prostate-specific membrane antigen expression and response to DNA damaging agents in prostate cancer
B Sheehan, A Neeb, L Buroni, A Paschalis… - Clinical Cancer …, 2022 - AACR
… We hypothesize that such a rational combination could reduce the heterogeneity of PSMA
expression and increase the efficacy of PSMA-directed treatments, which are changing …
expression and increase the efficacy of PSMA-directed treatments, which are changing …
[HTML][HTML] Heterogeneity of prostate-specific membrane antigen (PSMA) and PSMA-ligand uptake detection combining autoradiography and postoperative pathology in …
H Wang, M Remke, T Horn, K Schwamborn, Y Chen… - EJNMMI research, 2023 - Springer
… that prostate cancer is a heterogeneous disease, and intratumor heterogeneity in IHC has no
correlation with heterogeneous 99m … Similarly, Paschalis et al. reported the heterogeneous …
correlation with heterogeneous 99m … Similarly, Paschalis et al. reported the heterogeneous …
Expression of prostate-specific membrane antigen in normal, benign, and malignant prostate tissues
GL Wright Jr, C Haley, ML Beckett… - … Oncology: Seminars and …, 1995 - Elsevier
… In contrast to PSA, PSMA expression was often heterogeneous with variable staining patterns,
… to die of prostate cancer in 1994, making deaths from prostate cancer second only to lung …
… to die of prostate cancer in 1994, making deaths from prostate cancer second only to lung …
Biological determinants of PSMA expression, regulation and heterogeneity in prostate cancer
… Occurring concurrently with the development of new AR inhibitory strategies, the discovery
of prostate-specific membrane antigen (PSMA) as a target for molecular imaging and …
of prostate-specific membrane antigen (PSMA) as a target for molecular imaging and …
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