… we found that transplants of subrenal … prostate cancer metastasis model developed in this
study should be useful for investigations of mechanisms underlying prostate cancer metastasis …

… Further, the development of this in vivo transplant tumor model offers the possibilities to …
treatment of metastatic prostate cancer, and to investigate the process of spontaneous metastatic …

… when the tissue is cryopreserved before transplantation 27, 32 . These … of metastases to
the lung after implantation of a prostate … Histologically, the metastases presented as a gland …

… metastatic model of human prostate cancer developed by surgical orthotopic implantation of
green fluorescent protein (GFP)-expressing prostate cancer … Metastases in the transplanted …

… Sterile collagen scaffolds (3 × 3 × 3 mm3, Gelfoam; Pharmacia & Upjohn Co., New York, NY)
were used for the transplantation of human PCa cells. Immediately before transplantation, 2 …

… A second theory, based on Paget's ‘seed and soil’ hypothesis, 14 is supported by data from
an innovative transplant model in which the humanized nonobese diabetic/severe combined …

… established in our laboratory are being investigated for their metastatic capability by
orthotopic transplantation of tumor fragments in the dorsolateral lobe of the nude mouse …

… In this review we summarize the properties of the prostate cancer model systems in use and
defined … seeking models with which to test specific hypotheses pertaining to prostate cancer. …

… Understanding the mechanism of prostate cancer metastasis is … on the development of a
clinically relevant in vivo model. … a model by using orthotopic implantation of human prostate …

… vivo models of prostate cancer metastasis include syngeneic rodent cancers and xenografts
of human cancer in … of osseous metastases in these models is rare, and in xenograft models, …