[HTML][HTML] An orthotopic metastatic prostate cancer model in SCID mice via grafting of a transplantable human prostate tumor line

Y Wang, H Xue, JC Cutz, J Bayani, NR Mawji… - Laboratory …, 2005 - Elsevier
… of a new in vivo model system for metastatic prostate cancer. Pieces of prostate cancer
tissue from a patient were grafted in testosterone-supplemented male NOD-SCID mice at the …

A metastatic and androgen-sensitive human prostate cancer model using intraprostatic inoculation of LNCaP cells in SCID mice

N Sato, ME Gleave, N Bruchovsky, PS Rennie… - Cancer research, 1997 - AACR
prostate cancer model with differentiated features using the human LNCaP cell line. Athymic
and SCID mice … Changes in serum and tumor PSA mRNA levels were determined before …

A Nod Scid mouse model to study human prostate cancer

C Bastide, C Bagnis, P Mannoni, J Hassoun… - … cancer and prostatic …, 2002 - nature.com
prostate cancer but without orthotopic implantation. In the present study, the Nod Scid mouse
has been used for subcutaneous and orthotopic implantation of human prostate carcinoma

Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID mice

KA Klein, RE Reiter, J Redula, H Moradi, XL Zhu… - Nature medicine, 1997 - nature.com
tumor model systems, including those for prostate cancer, is … that prostate cancer cells circulate
in the blood of these mice and … to reports detecting prostate cancer cells circulating in the …

… human prostate cancer cell xenografts in bone: Induction of osteoblastic reaction by prostate‐specific antigen‐producing tumors in athymic and SCID/bg mice using …

TT Wu, RA Sikes, Q Cui, GN Thalmann… - … journal of cancer, 1998 - Wiley Online Library
model for prostate cancer cells in intact athymic or SCID/bg mice using an intraosseous route
of tumor … A fresh human prostate cancer xenograft, when implanted sc in SCID mice, has …

Mouse models of prostate cancer

KC Valkenburg, BO Williams - Prostate cancer, 2011 - Wiley Online Library
mouse models used to study prostate cancer. We also comment on how closely each model
recapitulates human prostate cancer… properties of the SCID model, SCID mice were crossed …

Anti‐PSMA immunotoxin as novel treatment for prostate cancer? High and specific antitumor activity on human prostate xenograft tumors in SCID mice

P Wolf, K Alt, P Bühler, A Katzenwadel… - … Prostate, 2008 - Wiley Online Library
… in a SCID-mouse C4-2 xenograft model. C42 is a subline of the human prostate cancer cell
… , these cells represent a valuable model for hormone-refractory advanced human prostate

Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell‐line specific manner, through paradoxical effects on oncogenic pathways

JC Klink, AK Tewari, EM Masko, J Antonelli… - … Prostate, 2013 - Wiley Online Library
… SIRT1 activation by resveratrol deacetylates FOXO1, typically inhibiting apoptosis in PTEN
wt prostate cancer models 39. Since LAPC-4 is PTEN wt, apoptosis is inhibited, and thus you …

RNA interference targeting PSCA suppresses primary tumor growth and metastasis formation of human prostate cancer xenografts in SCID mice

Z Zhao, J He, R Kang, S Zhao, L Liu, F Li - The Prostate, 2016 - Wiley Online Library
… In the present study, we used mouse xenograft models to study the effects of PSCA expression
on PCa cells tumorigenesis in vivo. Our results showed that siRNA-PSCA transfection …

Current mouse and cell models in prostate cancer research

X Wu, S Gong, P Roy-Burman, P Lee… - … -related cancer, 2013 - erc.bioscientifica.com
Mouse models of prostate cancer (PCa) are critical for … Here, we summarize recent
advances in PCa mouse models … In ten SCID mice with primary tumors, followed for 12 weeks, …