过去一年中添加的文章,按日期排序

Drug-repurposing screen identifies thiostrepton as a novel regulator of the tumor suppressor DAB2IP

R De Florian Fania, S Maiocchi, R Klima, V Pellegrini… - bioRxiv, 2024 - biorxiv.org
3 天前 - … this protein an interesting target for anti-cancer therapy. Based on … to generate two
prostate cancer cell models in which … molecular mechanism underlying its anti-tumoral action. …

Darolutamide-Mediated Phospholipid Remodeling Induces Ferroptosis Through the Srebp1-Fasn Axis in Prostate Cancer

H Huang, B Li, B Cheng, H Huang, S Huang… - Available at SSRN … - papers.ssrn.com
4 天前 - … PCa and the effect of … antitumor effect of combination therapy with darolutamide
and ferroptosis inducers (FINs) was confirmed in PCa organoids and a mouse xenografts model

[HTML][HTML] The significance of the apelinergic system in doxorubicin-induced cardiotoxicity

K Matusik, K Kamińska, A Sobiborowicz-Sadowska… - Heart Failure …, 2024 - Springer
9 天前 - … Further research in chronic preclinical models is needed to confirm this hypothesis
and understand the mechanism of action for the apelinergic system. This review aims to …

Antioxidative, antimicrobial and anticancer evaluation of olive Olea europaea L. leaf extract

E Zandona, A Zandona, I Cindrić, K Hanousek Čiča… - FEBS Open Bio, 2024 - croris.hr
13 天前 - anticancer activity, we tested OLE effect on the breast (MDA-MB-231 and MCF-7)
and prostate (PC-3) cancer-type cell models. After 24h treatment the highest anticancer effect

AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications

AC Pippione, C Vigato, C Tucciarello… - ACS Medicinal …, 2024 - ACS Publications
16 天前 - … this activity into a pronounced antiproliferative effect in the 22RV1 prostate cancer
cell model. … The evaluation of potent antitumor activities of shikonin coumarin-carboxylic acid, …

Prostate tissue ablation and drug delivery by an image-guided injectable ionic liquid in ex vivo and in vivo models

YM Demirlenk, H Albadawi, Z Zhang, D Atar… - Science Translational …, 2024 - science.org
17 天前 - … vivo murine prostate tumor models. In vivo studies in canine models further demonstrated
… of this therapeutic for benign prostatic hyperplasia and prostate cancer. —Molly Ogle …

The correlation between TRIM28 expression and immune checkpoints in CRPC

D Xue, Q Zuo, J Chang, X Wu - The FASEB Journal, 2024 - Wiley Online Library
17 天前 - … the anti- tumor immune response of prostate cancer through … groups of mouse models
to study prostate cancer: the oe- NC + … We generated a prostate cancer mouse model with …

… -CD40 antibodies delivered via immunogenic biomaterials, and immune checkpoint inhibitors to optimize abscopal responses in preclinical models of prostate cancer

J Wirtz - 2024 - oparu.uni-ulm.de
17 天前 - … effects in our PCa model, demonstrated by the delayed tumor growth on both, the
anti-tumor response when combined with local anti-CD40. In our studies an abscopal effect

[HTML][HTML] New 3-(Dibenzyloxyphosphoryl) isoxazolidine Conjugates of N1-Benzylated Quinazoline-2, 4-diones as Potential Cytotoxic Agents against Cancer Cell Lines

M Łysakowska, IE Głowacka, E Honkisz-Orzechowska… - Molecules, 2024 - mdpi.com
23 天前 - anticancer activity against three tumor cell lines. All the tested compounds exhibited
high activity against the prostate cancer … , HepG2, and HSF cellular models at all the tested …

[HTML][HTML] Exploring the therapeutic mechanism of curcumin in prostate cancer using network pharmacology and molecular docking

J Li, X Wang, X Li, Q He - Heliyon, 2024 - cell.com
31 天前 - … in preclinical models of tumours. However, its mechanism of action in prostate
cancer … and c-myc, which further enhances its anti-cancer effect. Notably, inhibition of miR-34a …