… The present study shows that in prostate cancer models, sHA has potent antitumor activity
with desirable toxicity profile and ease of detection in serum. In fact, more than 60% of the …

… antitumor activity of EZN-4176 in both androgen-sensitive and castration-resistant tumor
models. … To show that the antitumor effect was associated with the AR status, we treated mice …

… of anticancer drugs for prostate cancer.13 Specific studies carried out on some … prostate
cancer tumor growth in vivo, showing outstanding antitumor activity in a xenograft model…

… 5 and 10 mg/kg/day of meclofenamic acid was administered for 25 days to a nude-mouse
model of human prostate cancer in order to evaluate the drug’s antitumor effect. Tumor growth …

… To examine the effect of S. virgaurea on tumor growth in mice, we used the rat prostatic
tumor model (AT6.1) in SCID mice (16). After injection of AT6.1 into the flank of the mice, the G-…

… effect in ProHA × TRAMP mice, suggesting either a direct antitumor effect or, perhaps more
interestingly, an effect … -depleting effect from other possible mechanisms of action is difficult, …

… antitumor activity in several human solid-tumor models. In this study, the in vitro and in vivo
antitumor … (DENSpm) in human prostate carcinoma cells was examined. METHODS. The …

… (SE) and crocin (CR) exhibit anticancer activity by promoting cell cycle arrest in prostate …
-derived compounds maintain a differentiated state of prostate cancer cells, we analyzed the …

… molecules with anticancer activity against prostate cancer, 1,2,4triazole/thioether hybrid
molecules of flurbiprofen derivatives were prepared. Because of the binding mode of action of …

… Computational modeling suggested that scoparone might bind the SH2 domain of STAT3…
anti-tumor effect against DU145 prostate cancer cells in part through inhibition of STAT3 activity…