Model systems of prostate cancer: uses and limitations

NM Navone, CJ Logothetis… - Cancer and metastasis …, 1998 - Springer
… of prostate cancer progression. In this review we summarize the properties of the prostate
cancer model … This review will guide the investigator seeking models with which to test specific …

[HTML][HTML] Current mouse and cell models in prostate cancer research

X Wu, S Gong, P Roy-Burman, P Lee… - … -related cancer, 2013 - erc.bioscientifica.com
… Mouse models of prostate cancer (PCa) are critical for understanding the biology of PCa …
Here, we summarize recent advances in PCa mouse models that led to new insights into …

Mouse models of prostate cancer: picking the best model for the question

MM Grabowska, DJ DeGraff, X Yu, RJ Jin… - Cancer and Metastasis …, 2014 - Springer
… of Health Mouse Models of Human Cancer Consortium initiated the Prostate Steering … )
models of prostate cancer (PCa). Today, a PubMed search for “prostate cancer mouse model” …

A preclinical xenograft model of prostate cancer using human tumors

…, Australian Prostate Cancer BioResource… - Nature protocols, 2013 - nature.com
… and prognosis of prostate cancer 17,18 . Although many models of prostate cancer only focus
on the epithelial tumor cells, … Cancer-associated fibroblasts (CAFs) isolated from human …

[HTML][HTML] Mouse models of prostate cancer

KC Valkenburg, BO Williams - Prostate cancer, 2011 - ncbi.nlm.nih.gov
… human patients afflicted with prostate cancer as well as those … models used to study prostate
cancer. We also comment on how closely each model recapitulates human prostate cancer

The current state of preclinical prostate cancer animal models

KJ Pienta, C Abate‐Shen, DB Agus, RM Attar… - … Prostate, 2008 - Wiley Online Library
… in each lab prior to the use of the model of interest. Each publication with a prostate cancer
model needs to standardize the models used with existent molecular/phenotypic data. …

A transgenic mouse prostate cancer model

JR Gingrich, NM Greenberg - Toxicologic pathology, 1996 - journals.sagepub.com
… , and metastasis of prostate cancer has been slow, largely due to the scarcity of adequate
animal model systems that reproduce the spectrum of human prostatic disease. Therefore, we …

Modeling prostate cancer in mice: limitations and opportunities

PJ Hensley, N Kyprianou - Journal of andrology, 2012 - Wiley Online Library
… value in the development of knockout models to study human … use of mouse models to
study prostate cancer progression to … relevant in vivo models of prostate cancer for therapeutic …

Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology …

M Ittmann, J Huang, E Radaelli, P Martin, S Signoretti… - Cancer research, 2013 - AACR
… of improved models of prostate cancer has already accelerated our understanding of the
complex biology of prostate cancer and promises … Cancer Res; 73(9); 2718–36. ©2013 AACR. …

[HTML][HTML] In vitro and in vivo model systems used in prostate cancer research

D Cunningham, Z You - Journal of biological methods, 2015 - ncbi.nlm.nih.gov
… The incidence of prostate cancer (PCa) is one of the most prevalent cancer diagnoses
throughout the world, and is one of the most intensely studied problems in human disease. …