Efficacy and safety of enzalutamide versus bicalutamide for patients with metastatic prostate cancer (TERRAIN): a randomised, double-blind, phase 2 study

ND Shore, S Chowdhury, A Villers, L Klotz… - The Lancet …, 2016 - thelancet.com
… TERRAIN was a double-blind, randomised phase 2 study, that recruited asymptomatic or
minimally symptomatic men with prostate cancer progression on androgen-deprivation therapy …

Enzalutamide monotherapy in hormone-naive prostate cancer: primary analysis of an open-label, single-arm, phase 2 study

B Tombal, M Borre, P Rathenborg, P Werbrouck… - The lancet …, 2014 - thelancet.com
… with hormone-naive prostate cancer of varying severity provides a level of disease suppression,
… response and outcomes with enzalutamide in non-castrate men with prostate cancer. …

Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer

KJ Pienta, JP Machiels, D Schrijvers, B Alekseev… - Investigational new …, 2013 - Springer
… Methods In a phase 2, open-label study, patients with … cancer had 50 % CA125 decline and
SD for 10 months with 0.3 mg/kg. We report herein findings from a single-arm, phase 2 trial to …

A prospective single-arm phase 2 study of stereotactic magnetic resonance guided adaptive radiation therapy for prostate cancer: early toxicity results

AME Bruynzeel, SU Tetar, SS Oei, S Senan… - International Journal of …, 2019 - Elsevier
… We performed a prospective phase 2 study of MRgRT for localized prostate cancer to …
studied using both clinician-scored and patient-reported outcomes. A nonrandomized phase 2

[HTML][HTML] … and antitumor activity of apalutamide (ARN-509), a potent androgen receptor antagonist, in the high-risk nonmetastatic castration-resistant prostate cancer …

MR Smith, ES Antonarakis, CJ Ryan, WR Berry… - European urology, 2016 - Elsevier
… The phase 2 portion of the study evaluates apalutamide activity … We report the phase 2 results
for patients in the nmCRPC … In this phase 2 study of apalutamide, we confirm the safety and …

… genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial

B Lazarevic, G Boezelijn, LM Diep, K Kvernrod… - … and cancer, 2011 - Taylor & Francis
… -blind Phase 2 study to examine the effect of 30 mg synthetic genistein daily on serum and
tissue biomarkers in patients with localized prostate cancer (CaP). Fifty-four study subjects …

Olaparib combined with abiraterone in patients with metastatic castration-resistant prostate cancer: a randomised, double-blind, placebo-controlled, phase 2 trial

N Clarke, P Wiechno, B Alekseev, N Sala… - The Lancet …, 2018 - thelancet.com
phase 2 study, the efficacy of olaparib monotherapy in patients with advanced prostate cancer
was … A phase 2 trial of veliparib in combination with abiraterone in patients with metastatic …

Combination of bevacizumab and docetaxel in docetaxel-pretreated hormone-refractory prostate cancer: a phase 2 study

G Di Lorenzo, WD Figg, SD Fossa, V Mirone… - European urology, 2008 - Elsevier
Cancer Society has estimated that, during 2007, about 218,890 new cases of prostate cancer
will be … In this respect, a randomized phase 2 study comparing docetaxel alone versus the …

Phase 2 study of neoadjuvant docetaxel plus bevacizumab in patients with high‐risk localized prostate cancer: A Prostate Cancer Clinical Trials Consortium trial

RW Ross, MD Galsky, P Febbo, M Barry, JP Richie… - Cancer, 2012 - Wiley Online Library
… We previously reported a phase 2 study of neoadjuvant docetaxel before RP in 19 men with
high-risk localized PCa, demonstrating that treatment was well tolerated and associated with …

A phase 2 study of carboplatin plus docetaxel in men with metastatic hormone‐refractory prostate cancer who are refractory to docetaxel

RW Ross, TM Beer, S Jacobus… - Cancer …, 2008 - Wiley Online Library
… HRPC have demonstrated both a high prostate-specific antigen (PSA) … a single-arm, phase
2 trial of docetaxel plus carboplatin … the neuroendocrine phenotype in prostate cancer and its …