[HTML][HTML] … therapy to external beam radiotherapy in patients with localised intermediate-risk prostate cancer: a randomised, open-label, parallel-group phase 2 trial

DP Dearnaley, DR Saltzstein, JE Sylvester, L Karsh… - European Urology, 2020 - Elsevier
… suppression and recovery, PSA levels, prostate volume, quality of life (QoL), and … study to
serve as a contemporary ADT benchmark for qualitative comparisons. A second phase 2 study

Effects of cabozantinib on pain and narcotic use in patients with castration-resistant prostate cancer: results from a phase 2 nonrandomized expansion cohort

E Basch, KA Autio, MR Smith, AV Bennett… - European urology, 2015 - Elsevier
… This phase 2 NRE cohort implemented key elements desired … study design of, the blinded,
randomized, phase 3 COMET-2 … to a phase 2 signal-seeking study, was an essential step in …

Phase I/II study of bortezomib plus docetaxel in patients with advanced androgen-independent prostate cancer

R Dreicer, D Petrylak, D Agus, I Webb, B Roth - Clinical cancer research, 2007 - AACR
… In vitro and in vivo studies of prostate cancer and other solid tumors suggest that bortezomib
activity is … A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. …

Phase II multicenter study of abiraterone acetate plus prednisone therapy in patients with docetaxel-treated castration-resistant prostate cancer

DC Danila, MJ Morris, JS De Bono, CJ Ryan… - Journal of Clinical …, 2010 - ascopubs.org
study is the second trial showing the activity of AA in patients with castration-resistant
prostate cancer … under evaluation in two prospective randomized, phase III, placebo-controlled …

Results of a prospective phase 2 pilot trial of 177Lu–PSMA-617 therapy for metastatic castration-resistant prostate cancer including imaging predictors of treatment …

L Emmett, M Crumbaker, B Ho, K Willowson… - … genitourinary cancer, 2019 - Elsevier
… Lu that target PSMA have shown good efficacy and low toxicity in a recent prospective phase
2 study 1 and in multiple retrospective studies in men with mCRPC.2, 3, 4, 5, 8, 9, 10, 11, 12…

[177Lu] Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial

MS Hofman, L Emmett, S Sandhu, A Iravani… - The Lancet, 2021 - thelancet.com
… to metastatic castration-resistant prostate cancer. This phase 2 study provides evidence that
[ 177 … in men with metastatic castration-resistant prostate cancer, with greater activity but less …

The multicenter, randomized, phase 2 PEACE V-STORM trial: defining the best salvage treatment for oligorecurrent nodal prostate cancer metastases

T Zilli, P Dirix, R Heikkilä… - European …, 2021 - eu-focus.europeanurology.com
… observed in prostate cancer (PCa) patients relapsing after a primary curative treatment [ …
from all patients before inclusion in the study. This study was approved by the ethics committee …

Phase 2 multicenter study of gantry-based stereotactic radiotherapy boost for intermediate and high risk prostate cancer (PROMETHEUS)

D Pryor, M Sidhom, S Arumugam, J Bucci… - Frontiers in …, 2019 - frontiersin.org
… in escalating above the current 20 Gy in 2 fraction dose level. The low PSA nadirs in this
study are similar to that reported in previous studies utilizing SBRT boosts and not dissimilar to …

Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone‐refractory prostate cancer

…, M Carducci, Atrasentan Phase 3 Study Group - Cancer, 2008 - Wiley Online Library
… In placebo-controlled, phase 2 and 3 clinical trials in patients with asymptomatic or
symptomatic. metastatic HRPC, atrasentan delayed disease progression and PSA progression, …

EAU guidelines on prostate cancer. Part II: Treatment of advanced, relapsing, and castration-resistant prostate cancer

N Mottet, J Bellmunt, M Bolla, S Joniau… - Actas Urológicas …, 2011 - Elsevier
… Many studies have been conducted on the use of RT for PSA-only recurrence following RP.
As confirmed by various studies, the preradiation PSA level is critically important for optimal …