A preclinical xenograft model of prostate cancer using human tumors
…, Australian Prostate Cancer BioResource… - Nature protocols, 2013 - nature.com
… and prognosis of prostate cancer 17,18 . Although many models of prostate cancer only focus
on the epithelial tumor cells, … Cancer-associated fibroblasts (CAFs) isolated from human …
on the epithelial tumor cells, … Cancer-associated fibroblasts (CAFs) isolated from human …
The current state of preclinical prostate cancer animal models
… (1) Create a virtual systematic database for reagents, methods, characteristics, and
controls for cell lines, xenograft models, and GEM models. This type of database would allow …
controls for cell lines, xenograft models, and GEM models. This type of database would allow …
Use of nude mouse xenograft models in prostate cancer research
WM van Weerden, JC Romijn - The Prostate, 2000 - Wiley Online Library
… of human prostate tumor xenograft models, and large numbers of clinical prostate tumors …
This applies to both fundamental as well as preclinical studies. Besides the significance of …
This applies to both fundamental as well as preclinical studies. Besides the significance of …
Preclinical models of prostate cancer: patient-derived xenografts, organoids, and other explant models
GP Risbridger, R Toivanen… - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
… prostate cancer field is hampered by the limited number of human cell lines and xenograft
models… xenograft, organoid, and other explant models to address this need. In contrast to other …
models… xenograft, organoid, and other explant models to address this need. In contrast to other …
A preclinical xenograft model identifies castration-tolerant cancer-repopulating cells in localized prostate tumors
…, Australian Prostate Cancer BioResource… - Science translational …, 2013 - science.org
… In conclusion, in an experimental model for engrafting localized prostate cancer specimens,
a subset of tumor cells persisted during long-term castration and regenerated the tumor …
a subset of tumor cells persisted during long-term castration and regenerated the tumor …
Mouse models in prostate cancer translational research: from xenograft to PDX
D Rea, V Del Vecchio, G Palma… - BioMed research …, 2016 - Wiley Online Library
… To date, preclinical prostate cancer mouse models still represent an essential tool to improve
our … The xenograft models represent a great tool to study the mechanisms underlying many …
our … The xenograft models represent a great tool to study the mechanisms underlying many …
[HTML][HTML] Development of patient-derived xenograft models of prostate cancer for maintaining tumor heterogeneity
C Shi, X Chen, D Tan - Translational andrology and urology, 2019 - ncbi.nlm.nih.gov
… PDOs, grown in 3D culture with dissociated cells, is a novel pre-clinical model system in
oncology that allows ex vivo propagation of tumors from individual patients (52). This 3D culture …
oncology that allows ex vivo propagation of tumors from individual patients (52). This 3D culture …
Preclinical mouse models of human prostate cancer and their utility in drug discovery
SI Park, SJ Kim, LK McCauley… - Current protocols in …, 2010 - Wiley Online Library
… models and human prostate cancer xenograft mouse models. In contrast to transgenic
mouse models … Therefore, the data generated from human prostate cancer xenograft models …
mouse models … Therefore, the data generated from human prostate cancer xenograft models …
Application of prostate cancer models for preclinical study: advantages and limitations of cell lines, patient-derived xenografts, and three-dimensional culture of patient …
T Namekawa, K Ikeda, K Horie-Inoue, S Inoue - Cells, 2019 - mdpi.com
… preclinical model cell lines and their sublines, PDXs, and patient-derived organoid and
spheroid models… have summarized PCa PDX models, especially xenograft models, produced by …
spheroid models… have summarized PCa PDX models, especially xenograft models, produced by …
Next generation patient-derived prostate cancer xenograft models
D Lin, H Xue, Y Wang, R Wu, A Watahiki… - Asian journal of …, 2014 - journals.lww.com
… vivo prostate cancer tissue xenograft models. Following a short overview of various types of
prostate cancer models… More realistic preclinical models for prostate cancer are thought to be …
prostate cancer models… More realistic preclinical models for prostate cancer are thought to be …
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