Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set

SN Thibodeau, AJ French, SK McDonnell… - Nature …, 2015 - nature.com
… data set to previously identified prostate cancer (PrCa)-risk SNPs in an effort to … risk SNPs,
including all SNPs in linkage disequilibrium with each risk SNP, resulting in 100 unique risk

Prostate cancer (PCa) risk variants and risk of fatal PCa in the national cancer institute breast and prostate cancer cohort consortium

IM Shui, S Lindström, AS Kibel, SI Berndt, D Campa… - European urology, 2014 - Elsevier
… We found that 22 of the risk SNPs were significantly associated with the risk of fatal PCa (p
< 0.05) and that the magnitude and direction of the majority of the ORs for fatal PCa compared …

Individual and cumulative effect of prostate cancer risk‐associated variants on clinicopathologic variables in 5,895 prostate cancer patients

AK Kader, J Sun, SD Isaacs, KE Wiley, G Yan… - … Prostate, 2009 - Wiley Online Library
… (SNPs) have been associated with prostate cancer (PCa) risk … Twenty PCa risk SNPs
implicated in GWAS and fine mapping … We tested the cumulative effects of PCa risk SNPs on PCa …

Sequence variants at 22q13 are associated with prostate cancer risk

J Sun, SL Zheng, F Wiklund, SD Isaacs, G Li, KE Wiley… - Cancer research, 2009 - AACR
… In this report, we describe a novel prostate cancer risk-associated SNP that was … prostate
cancer risk with all the genotyped and imputed SNPs in the 1 Mb region flanking the SNP

Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer

H Guo, M Ahmed, F Zhang, CQ Yao, SD Li, Y Liang… - Nature …, 2016 - nature.com
prostate cancer risk-associated SNPs are largely unknown. As with most other diseases and
traits, these risk-associated SNPs … Here we show that prostate cancer risk-associated SNPs

Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers—results from BPC3

S Lindstrom, F Schumacher, A Siddiq, RC Travis… - PloS one, 2011 - journals.plos.org
… replicated the association between prostate cancer risk and 36 SNPs identified in multi-stage
genome-wide association studies of prostate cancer. Except for SNPs in KLK3 that were …

Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 cohort study

M Aly, F Wiklund, J Xu, WB Isaacs, M Eklund… - European urology, 2011 - Elsevier
… of prostate-specific antigen (PSA) results in diagnostic biopsies in men without prostate cancer
(… We present evidence to show that SNPs can be used in a specific and important clinical …

[HTML][HTML] Single nucleotide polymorphisms (SNPs) in prostate cancer: its implications in diagnostics and therapeutics

KS Allemailem, A Almatroudi, F Alrumaihi… - American journal of …, 2021 - ncbi.nlm.nih.gov
… could be utilized for the screening and management of prostate cancer. SNPs are predictors
of aggressive prostate cancer and in this review the research findings highlighted that SNPs

Plateau effect of prostate cancer risk‐associated SNPs in discriminating prostate biopsy outcomes

S Ren, J Xu, T Zhou, H Jiang, H Chen, F Liu… - … prostate, 2013 - Wiley Online Library
… A total of 667 consecutive patients that underwent prostate biopsy for detection of PCa at …
29 PCa risk‐associated SNPs. Performance of these genetic scores for discriminating prostate

Genetic predisposition to prostate cancer

S Benafif, R Eeles - British medical bulletin, 2016 - academic.oup.com
SNPs may contribute to cancer risk, for example, the identified SNP may in fact be in LD with
the causative SNP and … Alternatively, an SNP may cause a structural change in the promoter …