Identification of candidate genes for prostate cancer-risk SNPs utilizing a normal prostate tissue eQTL data set
SN Thibodeau, AJ French, SK McDonnell… - Nature …, 2015 - nature.com
… data set to previously identified prostate cancer (PrCa)-risk SNPs in an effort to … risk SNPs,
including all SNPs in linkage disequilibrium with each risk SNP, resulting in 100 unique risk …
including all SNPs in linkage disequilibrium with each risk SNP, resulting in 100 unique risk …
Prostate cancer (PCa) risk variants and risk of fatal PCa in the national cancer institute breast and prostate cancer cohort consortium
IM Shui, S Lindström, AS Kibel, SI Berndt, D Campa… - European urology, 2014 - Elsevier
… We found that 22 of the risk SNPs were significantly associated with the risk of fatal PCa (p
< 0.05) and that the magnitude and direction of the majority of the ORs for fatal PCa compared …
< 0.05) and that the magnitude and direction of the majority of the ORs for fatal PCa compared …
Individual and cumulative effect of prostate cancer risk‐associated variants on clinicopathologic variables in 5,895 prostate cancer patients
AK Kader, J Sun, SD Isaacs, KE Wiley, G Yan… - … Prostate, 2009 - Wiley Online Library
… (SNPs) have been associated with prostate cancer (PCa) risk … Twenty PCa risk SNPs
implicated in GWAS and fine mapping … We tested the cumulative effects of PCa risk SNPs on PCa …
implicated in GWAS and fine mapping … We tested the cumulative effects of PCa risk SNPs on PCa …
Sequence variants at 22q13 are associated with prostate cancer risk
J Sun, SL Zheng, F Wiklund, SD Isaacs, G Li, KE Wiley… - Cancer research, 2009 - AACR
… In this report, we describe a novel prostate cancer risk-associated SNP that was … prostate
cancer risk with all the genotyped and imputed SNPs in the 1 Mb region flanking the SNP …
cancer risk with all the genotyped and imputed SNPs in the 1 Mb region flanking the SNP …
Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer
… prostate cancer risk-associated SNPs are largely unknown. As with most other diseases and
traits, these risk-associated SNPs … Here we show that prostate cancer risk-associated SNPs …
traits, these risk-associated SNPs … Here we show that prostate cancer risk-associated SNPs …
Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers—results from BPC3
… replicated the association between prostate cancer risk and 36 SNPs identified in multi-stage
genome-wide association studies of prostate cancer. Except for SNPs in KLK3 that were …
genome-wide association studies of prostate cancer. Except for SNPs in KLK3 that were …
Polygenic risk score improves prostate cancer risk prediction: results from the Stockholm-1 cohort study
… of prostate-specific antigen (PSA) results in diagnostic biopsies in men without prostate cancer
(… We present evidence to show that SNPs can be used in a specific and important clinical …
(… We present evidence to show that SNPs can be used in a specific and important clinical …
[HTML][HTML] Single nucleotide polymorphisms (SNPs) in prostate cancer: its implications in diagnostics and therapeutics
… could be utilized for the screening and management of prostate cancer. SNPs are predictors
of aggressive prostate cancer and in this review the research findings highlighted that SNPs …
of aggressive prostate cancer and in this review the research findings highlighted that SNPs …
Plateau effect of prostate cancer risk‐associated SNPs in discriminating prostate biopsy outcomes
… A total of 667 consecutive patients that underwent prostate biopsy for detection of PCa at …
29 PCa risk‐associated SNPs. Performance of these genetic scores for discriminating prostate …
29 PCa risk‐associated SNPs. Performance of these genetic scores for discriminating prostate …
Genetic predisposition to prostate cancer
S Benafif, R Eeles - British medical bulletin, 2016 - academic.oup.com
… SNPs may contribute to cancer risk, for example, the identified SNP may in fact be in LD with
the causative SNP and … Alternatively, an SNP may cause a structural change in the promoter …
the causative SNP and … Alternatively, an SNP may cause a structural change in the promoter …
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