… well prostate … cancer aggressiveness and forestall the introduction of personalized
medicine.3 The aim of this study was to assess somatic heterogeneity of multifocal prostate cancer …

… somatic alterations in localized prostate cancer from the Cancer Genome Atlas (TCGA)
prostate cancer … Highly variable frequency of ERG alterations in 22 prostate cancer from …

… Likewise, we found that somatic alterations in BRCA2 were present … somatic BRCA2 loss
of function alterations occur early in tumorigenesis for affected patients. Conversely, alterations …

… Our results indicate that somatic alteration of TET2 occurs at a significant frequency in
mCRPC (Table 2, Fig. 3). The gene encodes a protein belonging to a family of three related …

… Early-onset prostate cancer (EO-PCA) represents the earliest clinical manifestation of
prostate cancer. To compare the genomic alteration landscapes of EO-PCA with “classical” (elderly…

… , somatic alterations and epigenetic phenomena involved in the pathogenesis of prostate
cancer. … on articles that investigated the contribution of somatic alterations to prostate cancer. …

… alterations … alterations may impact the response to CaP treatments such as ADT, radiation
therapy, and chemotherapy. Here, we review the contribution of recurring somatic alterations …

… altered in the germline of men with metastatic prostate cancer. … and somatic alterations in a
set of primary prostate tumors and … from 944 unique men with prostate cancer. Frequencies of …

… further insights into prostate cancer treatment and prevention. … and genomic alterations
(both inherited and somatic) and … prostate cancer is an important risk factor for prostate cancer; …

… a particular focus on recent studies on somatic alterations in PCa. … In contrast, somatic
alterations arise in prostate cells; these … This review will focus on somatic alterations in PCa. …