… cell may not be derived from the AR + secretory luminal population. An understanding of
the cell of origin of prostate cancers … the evolution to, androgen-refractory prostate cancer. …

… cellular origins of prostate cancer, we have looked for cells within prostate tumours that
expressed the prostate epithelial stem … normal prostate epithelial stem cells, the tumour stem cells …

… low–Gleason grade prostate cancer can be … prostate cancer, we know little about the target
cells for oncogenic change and, in particular, the tumor-initiating cell, both within the prostate …

… cells that are responsible for maintaining the tumor. We report … cancer stem cell population
from human prostate tumors, which possess a significant capacity for self-renewal. These cells …

… and functional properties of normal stem cells. Since the initial reports on … Prostate cancer
development is an evolutionary process that reflects an evolving of prostate cancer stem cells (…

… Here we review the current status of studies to identify CSCs in human prostate cancer as
… identification of prostate epithelial stem cells and cell types of origin for prostate cancer, and …

… of prostate cancer. This review discusses the embryonic prostate stem cell niche, normal
prostate … of normal prostate and prostate cancer stem cells, and current concepts on the origin of …

… Several solid tumors have now been shown to contain stem cell-like cells called cancer stem
cells (CSC). These cells, although generally rare, appear to be highly tumorigenic and may …

… In this review, we consider stem cells as cellular targets for prostate cancer therapies. To …
discuss prostatic stem cells during disease progression focusing on three specific types of cells, …

… incomplete depletion of tumor cells, resulting in tumor relapse. The cancer stem cell (CSC) …
disease as well as the tendency of cancers to relapse, metastasize, and develop resistance …