… In this review we summarize the properties of the prostate cancer model systems in use and
defined … seeking models with which to test specific hypotheses pertaining to prostate cancer. …

… and prognosis of prostate cancer 17,18 . Although many models of prostate cancer only focus
on the epithelial tumor cells, … Cancer-associated fibroblasts (CAFs) isolated from human …

… Mouse models of prostate cancer (PCa) are critical for understanding the biology of PCa …
Here, we summarize recent advances in PCa mouse models that led to new insights into …

… model of human prostate cancer offers an opportunity to dissect the molecular mechanisms
associated with the "natural history" of prostate cancer … of prostate tumor progression and to …

… this model, as searches on PubMed for the term “prostate cancer subrenal capsule” returns
31 hits. The majority of these publications are aimed at investigating the primary tumor itself …

… bone tumors … prostate cancer metastases developed in our model resembles the clinical
spectrum to some degree. Noting the exception of subcutaneous tumors developed in our model …

… To date, a number of different rodent prostate tumor models have … prostate cancer metastases
(see Alternate Protocol ). These models, combined with the autochthonous TRAMP model …

… Although prostatic metastasis to … model is unique in that it is the only model generated
with the Tag alone, thereby eliminating any influences of the small t antigen on prostate tumor …

… human patients afflicted with prostate cancer as well as those … models used to study prostate
cancer. We also comment on how closely each model recapitulates human prostate cancer…

… , and metastasis of prostate cancer has been slow, largely due to the scarcity of adequate
animal model systems that reproduce the spectrum of human prostatic disease. Therefore, we …