… We found that BADGE completely blocked the neuroprotective effect provided by arachidonic
acid, whereas MK886 did not abolish its protective effect. MK886 can directly protect …

… Linoleic acid (50 and 100 μM) significantly reduced MPP + -… The protective effect could
be mimicked by arachidonic acid, … that arachidonic acid is indeed protective. For example, …

… Hence, in view of the high level of oxidative stress and persistent inflammation associated
with AIL, in the present study, we firstly evaluated the protective effects of AA on PQ-induced …

… Arachidonic acid (AA), an intercellular messenger in the central nervous system, has been
reported to have multiple effects on glutamate receptors, including an inhibitory effect on non-…

… However, the effects of polyunsaturated fatty acids in … examined the effects of arachidonic
acid (AA) on palmitic acid (PA… acid (ETYA), a non-metabolizable AA, had little effect on PA-…

… Essential fatty acids (EFA) deficiency exerts a striking protective effect in several animal
models of autoimmune disease including diabetes mellitus. Lefkowith et al.reported that EFA …

… In conclusion, our data indicate that ARA has protective effects against cerebral ischemia/reperfusion
injury in rats, and the cerebroprotective effects may be mediated by antioxidant and …

… largely with regard to arachidonic acid metabolism in the vessel wall as well as platelets (1,
2). EPA is a substrate of cyclooxygenase (COX) in the arachidonate cascade, resulting in the …

… Our results provide new evidence of a protective effect of AA on astrocytes under OGD
conditions, suggesting that a low concentration of AA may protect against brain ischemic diseases…

… , suggesting that both LA and AA have similar, protective effects against cardiovascular
disease [17]. More work is needed to separate the effects of LA and AA on risk of cardiovascular …