Therapeutic and protective effect of environmental enrichment against psychogenic and neurogenic stress

C Fox, Z Merali, C Harrison - Behavioural brain research, 2006 - Elsevier
… following exposure to enrichment may be due to compensatory mechanisms mediated by
intact … involvement in the anxiolytic effect of environmental enrichment would be most helpful. …

Environmental enrichment increases glucocorticoid receptors and decreases GluA2 and protein kinase M zeta (PKMζ) trafficking during chronic stress: a protective …

RM Zanca, SH Braren, B Maloney… - Frontiers in behavioral …, 2015 - frontiersin.org
Environmental enrichment (EE) housing paradigms have long been shown beneficial for
brain … mechanism that is protective for retaining synaptic plasticity and memory function. …

Inoculation stress hypothesis of environmental enrichment

EJ Crofton, Y Zhang, TA Green - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
… stress hypothesis of environmental enrichment is to provide a … of the molecular mechanisms
underlying these protectiveEnvironmental enrichment produces protective phenotypes …

Molecular mechanisms underlying the neuroprotection of environmental enrichment in Parkinson's disease

TA Alarcón, SM Presti-Silva, APT Simões… - Neural Regeneration …, 2023 - journals.lww.com
… the molecular mechanisms underlying environmental enrichment … data showing how
environmental enrichment can act as a … the potential of environmental enrichment as an additional …

Neuroprotection and recovery from early-life adversity: considerations for environmental enrichment

AC Kentner - Neural regeneration research, 2015 - journals.lww.com
… EE offers protection against some consequences of both fetal and neonatal exposure to
LPS and a current line of inquiry continues to evaluate the components and mechanisms of EE …

Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

CJ Faherty, KR Shepherd, A Herasimtschuk… - Molecular brain …, 2005 - Elsevier
… These two experiments suggest that any neuronal protection occurs via a central
protection mechanism rather than by differences in peripheral detoxification or central MPTP …

Antidepressant and proneurogenic influence of environmental enrichment in mice: protective effects vs recovery

M Llorens-Martín, GS Tejeda, JL Trejo - Neuropsychopharmacology, 2011 - nature.com
Environmental enrichment (EE) induces brain activity known … We found that EE has a protective
effect in adult female mice (C57BL/… , and enrichment, and that form part of the mechanism

Early-life handling stimulation and environmental enrichment: are some of their effects mediated by similar neural mechanisms?

A Fernández-Teruel, L Giménez-Llort… - Pharmacology …, 2002 - Elsevier
environmental enrichment (EE) of laboratory rodents have been the two most commonly used
methods of providing supplementary environmental … and being “protective” against some …

Environmental enrichment cognitive neuroprotection in an experimental model of cerebral ischemia: biochemical and molecular aspects

LV Goncalves, AL Herlinger, TAA Ferreira… - Behavioural Brain …, 2018 - Elsevier
Enriched environment (EE) has been brought forward as a preconditioning method …
mechanisms involved in this tolerance are not yet clear. Herein we aimed to identify the mechanisms

Environmental enrichment protects against stress-induced anxiety: Role of glucocorticoid receptor, ERK, and CREB signaling in the basolateral amygdala

LS Novaes, NB Dos Santos, RFP Batalhote… - …, 2017 - Elsevier
Environmental enrichment (EE) is an experimental animal … However, the mechanisms by
which EE exerts its protective … of the mechanism by which EE exerts its protective effects against …