Teichoic acids, lipoteichoic acids and related cell wall glycopolymers of Gram-positive bacteria

T Kohler, G Xia, E Kulauzovic, A Peschel - Microbial glycobiology, 2010 - Elsevier
… Recent studies have yielded a growing picture of the biosynthetic pathways for the cell
wall-anchored wall teichoic acid (WTA) and the membrane-anchored lipoteichoic acid (LTA) in …

The length of lipoteichoic acid polymers controls Staphylococcus aureus cell size and envelope integrity

AR Hesser, LM Matano, CR Vickery… - Journal of …, 2020 - Am Soc Microbiol
… Here, we show that controlling the length of an essential cell envelope polymer, lipoteichoic
acid, is critical for controlling S. aureus cell size and cell envelope integrity. We also show …

[HTML][HTML] Lactobacillus plantarum possesses the capability for wall teichoic acid backbone alditol switching

PA Bron, S Tomita, II van Swam, DM Remus… - Microbial Cell …, 2012 - Springer
… polysaccharides, and extracellular proteins[2–… teichoic acid (WTA) is covalently anchored
to the MurN AC residue of peptidoglycan via a phosphodiester bond, whereas lipoteichoic acid

[HTML][HTML] Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase

FKK Li, FI Rosell, RT Gale, JP Simorre… - Journal of Biological …, 2020 - ASBMB
… Their cell walls are composed of a thick layer of peptidoglycan (PG) modified by the attachment
of wall teichoic acid (WTA), an anionic glycopolymer that is linked to pathogenicity and …

[HTML][HTML] Lipoteichoic Acid in Streptomyces hygroscopicus: Structural Model and Immunomodulatory Activities

M Cot, A Ray, M Gilleron, A Vercellone… - PloS one, 2011 - journals.plos.org
lipoteichoic acids or lipoglycans, whose functions and biosynthesis are not yet fully understood.
We report for the first time a detailed structure of lipoteichoic acid … amino-acid substituent. …

[HTML][HTML] Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics

EWC Sewell, ED Brown - The Journal of antibiotics, 2014 - nature.com
… Interestingly, wall teichoic acid biosynthetic proteins are encoded by … interactions in wall
teichoic acid synthesis has enabled the … compounds that block wall teichoic acid biogenesis in S. …

[HTML][HTML] Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae

N Heß, F Waldow, TP Kohler, M Rohde… - Nature …, 2017 - nature.com
… We propose that TacL is a lipoteichoic acid ligase acting in the final step of pnLTA synthesis
(Fig. 6). Our data are not consistent with the previously hypothesized role of SPD_1672 and …

The function of CozE proteins is linked to lipoteichoic acid biosynthesis in Staphylococcus aureus

MD Barbuti, E Lambert, IS Myrbråten, A Ducret… - Mbio, 2024 - Am Soc Microbiol
… In this work, we discover that a family of membrane proteins named CozE is involved in the
biosynthesis of lipoteichoic acids (LTAs) in S. aureus. CozE proteins have previously been …

Teichoic acids are temporal and spatial regulators of peptidoglycan cross-linking in Staphylococcus aureus

ML Atilano, PM Pereira, J Yates… - Proceedings of the …, 2010 - National Acad Sciences
protein 4 (PBP4) is required for the synthesis of this highly cross-linked peptidoglycan. We
found that wall teichoic acids, … , but in the absence of wall teichoic acids synthesis, it becomes …

Bifidobacteria cell wall-derived exo-polysaccharides, lipoteichoic acids, peptidoglycans, polar lipids and proteins–their chemical structure and biological attributes

M Pyclik, D Srutkova, M Schwarzer, S Gorska - International journal of …, 2020 - Elsevier
… , lipoteichoic acids, polar lipids, peptidoglycans and proteins. We discuss their involvement
in direct signaling to the host cells and their described immunomodulatory effects. …