Structural and functional diversity in Listeria cell wall teichoic acids

Y Shen, S Boulos, E Sumrall, B Gerber… - Journal of Biological …, 2017 - ASBMB
Wall teichoic acids (WTAs) are the most abundant glycopolymers found on the cell wall of
many Gram-positive bacteria, whose diverse surface structures play key roles in multiple …

Cryo-EM analysis of S. aureus TarL, a polymerase in wall teichoic acid biogenesis central to virulence and antibiotic resistance

FKK Li, LJ Worrall, RT Gale, ED Brown… - Science …, 2024 - science.org
… , and its synthesis is catalyzed by a set of teichoic acid glycerol (Tag) enzymes. The addition
… of not only WTA biogenesis but also the biogenesis of other glycoconjugates that rely on the …

Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria

MD Kattke, JE Gosschalk, OE Martinez, G Kumar… - PLoS …, 2019 - journals.plos.org
… Staphylococcus aureus and other bacterial pathogens affix wall teichoic acids (WTAs) to
their surface. These highly abundant anionic glycopolymers have critical functions in bacterial …

Lipoteichoic acid biosynthesis by Staphylococcus aureus is controlled by the MspA protein through competitive interference

D Bonini, S Duggan, A Alnahari, T Brignoli, H Strahl… - bioRxiv, 2023 - biorxiv.org
… layer and the anionic polymers lipoteichoic acid and wall teichoic acids, is fundamental for
… aureus virulence, contributes to the maintenance of normal levels of lipoteichoic acid in the …

Reconstitution of Staphylococcus aureus Lipoteichoic Acid Synthase Activity Identifies Congo Red as a Selective Inhibitor

CR Vickery, BMK Wood, HG Morris… - Journal of the …, 2018 - ACS Publications
lipoteichoic acid is made by lipoteichoic acid synthase (LtaS), a polytopic membrane protein
… (17a) Mutants lacking either ugtP or ltaA can still make lipoteichoic acid polymers, but LtaS …

Wall teichoic acids: physiology and applications

X Wu, J Han, G Gong, MAG Koffas… - FEMS Microbiology …, 2021 - academic.oup.com
… (ribitol phosphate), although they were named teichoic acids and were not differentiated from
lipoteichoic acids (LTAs, cell-membrane-associated teichoic acids) (Armstrong et al. 1958a,…

Mechanism of Staphylococcus aureus lipoteichoic acid length regulation, inhibition of wall teichoic acid biosynthesis, and physiology of teichoic acids

AR Hesser - 2020 - search.proquest.com
… biochemical analysis of teichoic acids will assist future efforts seeking … teichoic acid
biosynthesis. Together, this work provides a more complete picture of the functions of teichoic acids

Transcriptional regulation of TacL-mediated lipoteichoic acids biosynthesis by ComE during competence impacts pneumococcal transformation

M Yao, K Wang, G Song, Y Hu, J Chen, T Li… - Frontiers in Cellular …, 2024 - frontiersin.org
… The regulation of teichoic acid biosynthesis is tightly controlled during pneumococcal … We
demonstrated that a defect in lipoteichoic acid ligase (TacL)-mediated lipoteichoic acids (LTAs) …

Influence of Impaired Lipoprotein Biogenesis on Surface and Exoproteome of Streptococcus pneumoniae

T Pribyl, M Moche, A Dreisbach… - Journal of proteome …, 2014 - ACS Publications
… To estimate the proportion of pneumococcal surface proteins in the preparations, we
classified proteins according to their predicted localization. NSAFs derived from proteins of the …

Teichoic acids anchor distinct cell wall lamellae in an apically growing bacterium

E Ultee, LT van der Aart, L Zhang, D van Dissel… - Communications …, 2020 - nature.com
… PG, teichoic acids (TAs) 2,3 and a variety of capsular glycans 4,5,6,7 . Teichoic acids are long,
… and can be classified into wall teichoic acids (WTAs) and lipoteichoic acids (LTAs), based …