… The BCL-2 protein family principally determines whether a cell commits to apoptosis and
hence has … Consequently, alteration of this control can either promote cancer and autoimmune …

… the Bcl-2 proteins and the ways they regulate the apoptosis. … As Bcl-2 proteins are involved
in the control of apoptosis upstream of … on the role of Bcl-2 proteins in regulation of apoptosis. …

… -2 family proteins regulate apoptosis, leading to the notion that Bcl-2 family proteins constitute
… death decision point for cells in a common pathway involved in various forms of apoptosis. …

… IAP family via homology searches. One gene was identified which we termedlivin that encodes
a protein with … Expression of Livin inhibited apoptosis by a number of stimuli, whereas an …

… In this report, we show that overexpression of KIAP blocks apoptosis induced by menadione
… of KIAP enhances apoptosis induced by etoposide, and, that KIAP fails to block apoptosis in…

… mitochondrial apoptosis inducing factor (AIF) has been also found.The process of apoptosis
is … Inhibitor of apoptosis protein family (IAP) functions as inhibitors of caspasedependent cell …

… proteins form a growing family of death agonist and antagonist proteins that control apoptosis
… The death agonist (or proapoptotic) proteins include Bax, Bak, Bcl-Xs, Bad, Bid, Bik, Bim, …

… Active cellular suicide by apoptosis plays important roles in … A central step in the execution
of apoptosis is the activation of … these apparent differences in the control of cell death reflect …

… the as Bcl-2 family members [8]. A third group of factors, which consists of structurally related
proteins known as the inhibitor of apoptosis (IAP) family of proteins, possesses two unique …

… Despite the important role the Bcl-2 protein family plays in … -2 family of proteins modulates
apoptosis remains unclear. A possibility for the biochemical function of the Bcl-2 protein family …