Liver fatty acid-binding protein and obesity

BP Atshaves, GG Martin, HA Hostetler… - The Journal of nutritional …, 2010 - Elsevier
… and LCFA-CoAs to the nucleus for regulation of nuclear receptors important in transcription
of genes encoding proteins involved in LCFA and glucose metabolism [PPAR-α, HNF-4α, …

[HTML][HTML] Decreased liver fatty acid binding capacity and altered liver lipid distribution in mice lacking the liver fatty acid-binding protein gene

GG Martin, H Danneberg, LS Kumar… - Journal of Biological …, 2003 - ASBMB
… Although liver fatty acid-binding protein (L-FABP) is an important binding site for various …
fatty acid binding capacity, lipid composition, and expression of other lipid-binding proteins. Gel-…

[HTML][HTML] Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene

EP Newberry, Y Xie, S Kennedy, X Han… - Journal of Biological …, 2003 - ASBMB
Liver fatty acid-binding protein (L-Fabp) is an abundant cytosolic lipid-binding protein with
broad … and unsaturated fatty acids, we examined the fatty acid species present in hepatic free …

[HTML][HTML] Regulation of the Liver Fatty Acid-binding Protein Gene by Hepatocyte Nuclear Factor 1α (HNF1α): ALTERATIONS IN FATTY ACID HOMEOSTASIS INHNF1α …

TE Akiyama, JM Ward, FJ Gonzalez - Journal of Biological Chemistry, 2000 - ASBMB
… levels of fatty acid transporter gene expression was also observed. In contrast, there was
a marked reduction of liver fatty acid-binding protein (l-FABP) gene expression in the livers of …

[HTML][HTML] Liver fatty acid-binding protein gene ablation inhibits branched-chain fatty acid metabolism in cultured primary hepatocytes

BP Atshaves, AM McIntosh, OI Lyuksyutova… - Journal of Biological …, 2004 - ASBMB
… of liver fatty acid-binding protein (L-FABP) in the uptake, transport, mitochondrial oxidation,
and esterification of normal straight-chain fatty acids … of branched-chain fatty acids. Therefore, …

[HTML][HTML] Recent insights into the biological functions of liver fatty acid binding protein 1

GQ Wang, HL Bonkovsky, A de Lemos… - Journal of lipid …, 2015 - ASBMB
… since liver fatty acid binding protein (FABP)1 was first isolated. There are few protein families
… and yet new functions are being uncovered for this protein. FABP1 is known to be critical for …

Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

H Mitsuyoshi, K Yasui, Y Harano, M Endo… - Hepatology …, 2009 - Wiley Online Library
… : thioredoxin (Trx), fatty acid transport protein 5 (FATP5), sterol regulatory element-binding …
expression of genes involved in hepatic metabolism of fatty acids and iron using liver biopsy …

Hepatic phenotype of liver fatty acid binding protein gene-ablated mice

GG Martin, BP Atshaves, H Huang… - … and Liver …, 2009 - journals.physiology.org
… Effect of backcrossing on liver total cholesterol mass in liver fatty acid binding protein (L-FABP)
−/− mice. Lipid was extracted from liver homogenates of female (F) and male (M) mice as …

[PDF][PDF] A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation?

I Issemann, R Prince, J Tugwood… - Biochemical Society …, 1992 - researchgate.net
… FABP reporter genes The 5' regulatory sequences of the rat liver fatty acid binding protein
gene are shown schematically. The start of transcription is indicated with an arrow at + I and …

High dietary fat exacerbates weight gain and obesity in female liver fatty acid binding protein gene-ablated mice

BP Atshaves, AL McIntosh, SM Storey, KK Landrock… - Lipids, 2010 - Springer
… Since liver fatty acid binding protein (L-FABP) facilitates uptake/oxidation of long-chain
fatty … and/or obesity in response to high dietary fat. Male and female wild-type (WT) and L-FABP …