[HTML][HTML] Environmental enrichment increases glucocorticoid receptors and decreases GluA2 and protein kinase M zeta (PKMζ) trafficking during chronic stress: a …

RM Zanca, SH Braren, B Maloney… - Frontiers in behavioral …, 2015 - frontiersin.org
… We focus on two markers of synaptic plasticity and memory: the atypical protein kinase M …
KO mice demonstrate that another atypical kinase, the atypical protein kinase C iota/lambda (…

[HTML][HTML] The molecular effects of environmental enrichment on Alzheimer's disease

AKY Liew, CH Teo, T Soga - Molecular neurobiology, 2022 - Springer
environmental enrichment paradigm was first explored by Donald Hebb, who demonstrated
that socially enriched … For lab rodents, an enriched environment typically consists of larger …

Effects of environmental enrichment on gene expression in the brain

C Rampon, CH Jiang, H Dong… - Proceedings of the …, 2000 - National Acad Sciences
… Moreover, the cAMP-dependent protein kinase regulatory subunit was down-regulated
2.5-fold after 14 days of training. It has been shown that overexpression of this regulatory subunit …

Environmental enrichment during adolescence regulates gene expression in the striatum of mice

N Thiriet, L Amar, X Toussay, V Lardeux, B Ladenheim… - Brain research, 2008 - Elsevier
kinase kinase kinase 12 (MAP3K12) were also regulated by enriched environment. We have
mostly focused on these later genes because protein kinases and MAP kinases are known …

[HTML][HTML] Molecular mechanisms of environmental enrichment: impairments in Akt/GSK3β, neurotrophin-3 and CREB signaling

YS Hu, N Long, G Pigino, ST Brady, O Lazarov - PloS one, 2013 - journals.plos.org
… that environmental enrichment upregulates the Akt pathway, leading to the downregulation of
glycogen synthase kinaseProtein kinase B directly regulates GSK3β by phosphorylation of …

[HTML][HTML] Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens

CF Lichti, X Fan, RD English, Y Zhang, D Li… - Frontiers in behavioral …, 2014 - frontiersin.org
… Prior research demonstrated that environmental enrichment creates individual … Kinase
activity Another gene set robustly upregulated in EC rats is the GO gene set Protein kinase

Brief exposure to an enriched environment improves performance on the Morris water task and increases hippocampal cytosolic protein kinase C activity in young rats

R Paylor, SK Morrison, JW Rudy, LT Waltrip… - Behavioural brain …, 1992 - Elsevier
… AM and Alkon, DL, Protein kinase C redistribution within CA3 … and Sacktor, TC, The role
of protein kinase C in learning and … than postweaning environmental enrichment on maze …

Environmental enrichment enhances neurogranin expression and hippocampal learning and memory but fails to rescue the impairments of neurogranin null mutant …

FL Huang, KP Huang, J Wu… - Journal of …, 2006 - Soc Neuroscience
Environmental enrichment is known to enhance … Neurogranin (Ng), a specific substrate of
protein kinase C (PKC), is … -dependent protein kinase II (αCaMKII), PKC, protein kinase A (PKA)…

Environmental enrichment reverses tyrosine kinase inhibitor-mediated impairment through BDNF-TrkB pathway

H Bengoetxea, I Rico-Barrio, N Ortuzar… - Molecular …, 2018 - Springer
… factors examining cognitive, cellular, and molecular effects of exposure to environmental
enrichment on several brain areas after administration of a tyrosine kinase inhibitor. …

Environmental enrichment modifies the PKA-dependence of hippocampal LTP and improves hippocampus-dependent memory

SN Duffy, KJ Craddock, T Abel… - Learning & …, 2001 - learnmem.cshlp.org
… cAMP-dependent protein kinase (PKA) is critical for the expression of some forms of long-term
potentiation (LTP) in area CA1 of the mouse hippocampus and for hippocampus-…