… (JNKs) and extracellular signal-regulated kinase 5 (ERK5) … protein kinase (MAPKs) system.
The MAPKs are serine/threonine protein kinases that can be activated by ligands of G-protein…

… by protein kinase phosphatases. MAPK phosphatase (MKP)-2, 3, and 4 are probably the
protein kinase phosphatases most selective for ERK, although other phosphatases including …

… Protein kinase regulatory mechanisms must provide … The determination of crystal structures
of many protein kinases in … active protein kinase was of the catalytic domain of protein kinase …

… by members of the protein kinase C (PKC) gene family in the control of cell and tissue functions
has refocused efforts on the development of therapeutic interventions directed at specific …

… protein kinases as targets for chemotherapeutic intervention … might also be considered as
targets in the context of diseases … of inhibitors targeting protein kinases of parasitic protists, (iii) …

… Protein kinases and phosphatases are likely targets for the development of therapeutic drugs
since … interaction, and will provide additional molecular possibilities for drug intervention. …

… , and PRKX (the human X chromosome-encoded protein kinase X). PRKX was recently
described as a cAMP-dependent protein kinase that forms a cAMP sensitive holoenzyme with RI, …

… Abstract: Protein phosphorylation, mediated by protein kinases, has … protein components
of the phosphorylation process are protein kinases, protein target or substrate and protein …

… kinase targets. Efforts to develop compounds with greater specificity against a narrow subset
of kinases … conserved signature motif in essentially all kinase domains, it could be argued …

… contains the tyrosine kinase catalytic site.The major pathways activated by the EGFR are
the Ras/Raf/MAPK (mitogen-activated protein kinase)—ERK (extracellular regulated kinase). …