Stress-activated protein kinases: activation, regulation and function

A Paul, S Wilson, CM Belham, CJM Robinson… - Cellular signalling, 1997 - Elsevier
… of the stress-activated MAP kinase homologues, their role as components of parallel …
kinase pathways and the regulation of cellular responses following exposure to cellular stress

Protein kinase cascades activated by stress and inflammatory cytokines

JM Kyriakis, J Avruch - Bioessays, 1996 - Wiley Online Library
… mammalian stress-activated, ERK-based protein kinase … as the Stress-Activated Protein
Kinases (SAPKs, also referred to as the c-Jun a-terminal Kinases, JNKs)('r2), and the p38 kinase

The stress-activated protein kinase pathways

LA Tibbles, JR Woodgett - Cellular and Molecular Life Sciences CMLS, 1999 - Springer
… from the cell surface are transduced through the cytoplasm by a cascade of protein kinases.
… tyrosine phosphatase 2 (SHP-2) inactivates SAPK in response to cellular stress, but it is a …

Activation of protein kinase B (Akt/RAC‐protein kinase) by cellular stress and its association with heat shock protein Hsp27

H Konishi, H Matsuzaki, M Tanaka, Y Takemura… - FEBS …, 1997 - Wiley Online Library
… PKB activation, whereas protein synthesis inhibitors such as … stress-activated protein
kinase/c-Jun amino-terminal kinase … other cellular stress on the PKB activity by using COS-7 cells

The stress-activated protein kinase subfamily of c-Jun kinases

JM Kyriakis, P Banerjee, E Nikolakaki, T Dai, EA Rubie… - Nature, 1994 - nature.com
kinases activated by cellular stress and tumour necrosis factor (TNF)-a, hence they are
designated stress-activated protein kinases… , which elicits a subset of cellular responses to TNF-a (…

Regulation of the immune response by stress‐activated protein kinases

M Rincón, RJ Davis - Immunological reviews, 2009 - Wiley Online Library
kinase (SAPK) group was defined as group of kinases that activated by stimuli that cause
cell stress. In the immune cells, SAPKs are activated by antigen receptors (B- or T-cell receptors…

Stress-activated protein kinases in cardiovascular disease

T Force, CM Pombo, JA Avruch, JV Bonventre… - Circulation …, 1996 - Am Heart Assoc
… is the activation of protein kinases, which phosphorylate a host of cellular substrates, including
… The SAPKs are the predominant c-Jun kinases activated by many types of cellular stress. …

Mitogen-activated protein kinases in mammalian oxidative stress responses

C Runchel, A Matsuzawa, H Ichijo - Antioxidants & redox signaling, 2011 - liebertpub.com
… The ERK5 signaling pathway is activated by various factors, such as cellular stress (3), G
protein-coupled receptors (89), and growth factors (65). H 2 O 2 strongly activates ERK5 in …

Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress

KJ Cowan, KB Storey - Journal of Experimental Biology, 2003 - journals.biologists.com
… consists of three main protein kinase families: the extracellular signal-regulated protein
kinases (ERKs), the c-Jun N-terminal kinases (JNKs) and the p38 family of kinases. Each is …

Mitogen-activated protein kinases in apoptosis regulation

T Wada, JM Penninger - Oncogene, 2004 - nature.com
stress, mitogen-activated protein kinase (MAPK) family members are crucial for the maintenance
of cells. … cascades in response to many types of cellular stress, JNK activity is induced in …