[HTML][HTML] Cell-penetrating peptides in protein mimicry and cancer therapeutics
… require specificity of delivery to cancer cells, whilst sparing … including their incorporation
into therapeutic proteins. As the … to target specific protein–protein interactions integral to …
into therapeutic proteins. As the … to target specific protein–protein interactions integral to …
Vascular mimicry: Triggers, molecular interactions and in vivo models
SL Wechman, L Emdad, D Sarkar, SK Das… - Advances in cancer …, 2020 - Elsevier
… used cancer therapeutics are effective inhibitors of vascular mimicry, developing a new
class of vascular mimicry … of the pro vascular mimicry protein MMP-2. cAMP inhibits vascular …
class of vascular mimicry … of the pro vascular mimicry protein MMP-2. cAMP inhibits vascular …
Targeting vasculogenic mimicry by phytochemicals: a potential opportunity for cancer therapy
… Although numerous genes and proteins linked with VM have been reported previously,10
this review will focus on important phytochemicals that affect genes and proteins associated …
this review will focus on important phytochemicals that affect genes and proteins associated …
Foldamers as anticancer therapeutics: targeting protein–protein interactions and the cell membrane
S Fahs, Y Patil‐Sen, TJ Snape - ChemBioChem, 2015 - Wiley Online Library
… interactions is thought to be a potential strategy for cancer therapeutics. … proteins leads to
more versatile applications in drug design and therapeutic approaches, including the mimicry …
more versatile applications in drug design and therapeutic approaches, including the mimicry …
[HTML][HTML] Angiogenesis and vasculogenic mimicry as therapeutic targets in ovarian cancer
D Lim, Y Do, BS Kwon, W Chang, MS Lee, J Kim… - BMB …, 2020 - ncbi.nlm.nih.gov
… remarkable therapeutic effects in ovarian cancer patients. … are also used as ovarian cancer
therapeutics. Angiopoietin 1 … significantly correlated with VM and protein kinase Ca (PKCa…
therapeutics. Angiopoietin 1 … significantly correlated with VM and protein kinase Ca (PKCa…
Endogenous retroelements and the viral mimicry response in cancer therapy and cellular homeostasis
… levels as a cancer-specific therapeutic vulnerability that can be elevated by viral mimicry–inducing …
Improved understanding of viral mimicry signaling and tolerance mechanisms reveals …
Improved understanding of viral mimicry signaling and tolerance mechanisms reveals …
PRMT inhibition induces a viral mimicry response in triple-negative breast cancer
… breast cancer (TNBC) is the most aggressive breast cancer subtype with the worst prognosis
and few effective therapies. Here we identified MS023, an inhibitor of type I protein arginine …
and few effective therapies. Here we identified MS023, an inhibitor of type I protein arginine …
[HTML][HTML] Molecular mechanisms and anticancer therapeutic strategies in vasculogenic mimicry
X Zhang, J Zhang, H Zhou, G Fan, Q Li - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
… The discovery of vasculogenic mimicry (VM) provides a new therapeutic … PI3K proteins
are commonly found in a wide variety of cancers and have been … VM and cancer therapeutic …
are commonly found in a wide variety of cancers and have been … VM and cancer therapeutic …
White paper: mimetics of class 2 tumor suppressor proteins as novel drug candidates for personalized cancer therapy
E Dahl, S Villwock, P Habenberger, A Choidas, M Rose… - Cancers, 2022 - mdpi.com
… , we confirmed mimicry of tumor cell growth inhibition mediated by the recombinant VIT protein
only. In contrast, the vWA domain polypeptide did not significantly block cancer cell growth…
only. In contrast, the vWA domain polypeptide did not significantly block cancer cell growth…
Synthetic peptides as protein mimics
… mimicry of protein sites because such peptides can be generated as exact copies of protein
… laboratories in the use of synthetic protein mimics to modulate protein function, as well as to …
… laboratories in the use of synthetic protein mimics to modulate protein function, as well as to …
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