… protein palmitoylation in the various cancer types, and discuss the potential of targeting of
palmitoylation … Here we summarize recent findings on how protein palmitoylation affects key …

… of protein S-palmitoylation and focuses mainly on recent findings on the enzymes involved in
the process of palmitoylation … its implications for human diseases and therapeutic potential. …

… To most clearly illustrate the different ways in which protein palmitoylation can impact cancer,
we … Below, we describe how targeting protein palmitoylation could enhance the therapeutic …

… palmitoylation status of specific target proteins. Here, we consider the role that palmitoylation
… As yet, the therapeutic potential of blocking Ras palmitoylation has yet to be determined. …

… It has been demonstrated that membrane protein palmitoylation promotes their association
with cholesterol and sphingolipid-rich membrane microdomains or lipid rafts [85]. The lipid …

… In this review, we highlight recent progress in our understanding of protein lipidation, in
particular, S-palmitoylation and lysine fatty acylation, and we describe the importance of these …

… S-palmitoylation in immune regulation. Moreover, the therapeutic potential of targeting S-palmitoylation
in … In summary, protein palmitoylation regulates numerous immune pathways and …

… inhibitors would provide vital reagents with which to study the pathophysiological
importance of many palmitoylated proteins and may offer potential for therapeutic development. …

… palmitoylated proteins and palmitoyl acyltransferases (PATs) have the potential for therapeutic
… importance of protein palmitoylation in tumorigenic pathways. A new study has uncovered …

… Agents that alter the palmitoylation status of Ras, Wnt and Hh proteins have recently
been discovered, and represent the next generation of potential chemotherapeutics. …