Palmitoylation: a protein S-acylation with implications for breast cancer

AM Anderson, MA Ragan - NPJ breast cancer, 2016 - nature.com
… linking perturbation of palmitoylation cycling to metastatic disease involves two proteins that
… has been shown to modulate Wnt protein palmitoylation. ZDHHC2 is located at chromosome …

Protein palmitoylation modification during viral infection and detection methods of palmitoylated proteins

X Li, L Shen, Z Xu, W Liu, A Li, J Xu - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
… the acylation of viral or host proteins might be a strategy to … in protein palmitoylation have
been made to technological advances. This paper gives an overview of protein palmitoylation

Protein palmitoylation and its role in bacterial and viral infections

J Sobocińska, P Roszczenko-Jasińska… - Frontiers in …, 2018 - frontiersin.org
… bulk protein palmitoylation in eukaryotic cells (74), some proteins have a unique
autopalmitoylation activity. These include Bet3, a component of a multisubunit transport protein

Protein lipidation by palmitoylation and myristoylation in cancer

CW Fhu, A Ali - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
… relevance of protein lipidation, which can ultimately lead to identification of novel therapeutic
targets. In this review, we will cover the two most common protein lipidation, palmitoylation

Palmitoylation as a Signal for Delivery

Y Wang, H Lu, C Fang, J Xu - … and Cellular Mechanisms and Therapy, 2020 - Springer
… To facilitate future investigations on palmitoylation and immune checkpoints, here we …
roles of palmitoylation on protein stability, trafficking, membrane association, and proteinprotein

[HTML][HTML] Emerging roles of protein palmitoylation and its modifying enzymes in cancer cell signal transduction and cancer therapy

Z Liu, M Xiao, Y Mo, H Wang, Y Han… - … journal of biological …, 2022 - ncbi.nlm.nih.gov
Protein palmitoylationpalmitoylation modification on protein stability, localization and
downstream signal regulation, this review focuses on the regulatory roles of protein palmitoylation

Protein S‐Palmitoylation: advances and challenges in studying a therapeutically important lipid modification

A Main, W Fuller - The FEBS Journal, 2022 - Wiley Online Library
… With constantly improving pharmacological options, experimental models and
understanding of palmitoylation enzymology, our knowledge of the therapeutic relevance of the …

Dynamic protein acylation: new substrates, mechanisms, and drug targets

T Lanyon-Hogg, M Faronato, RA Serwa… - Trends in biochemical …, 2017 - cell.com
… , and understanding reversible protein palmitoylation dynamics has become a … therapeutic
potential. These chemical tools also complement biochemical methods to analyse protein

New insights into the mechanisms of protein palmitoylation

ME Linder, RJ Deschenes - Biochemistry, 2003 - ACS Publications
protein palmitoylation has been shown to have a role in protein−membrane interactions,
protein … machinery that carries out reversible palmitoylation of proteins has been elusive. In fact, …

Protein palmitoylation: Palmitoyltransferases and their specificity

S Tabaczar, A Czogalla, J Podkalicka… - Experimental …, 2017 - journals.sagepub.com
… S-palmitoylation of a substrate protein. Here, we discuss the topology of PAT proteins and
their … We will also give an overview of the mechanism of protein palmitoylation and how it is …