Filamentous fungi as cell factories for heterologous protein production

PJ Punt, N van Biezen, A Conesa, A Albers… - Trends in …, 2002 - cell.com
filamentous fungi have become preferred host organisms for protein production, and discuss
… hurdles that face further refinement of the production of non-fungal proteins by fungal hosts. …

Heterologous protein production in filamentous fungi

D Liu, S Garrigues, RP de Vries - Applied microbiology and biotechnology, 2023 - Springer
… of filamentous fungi as hosts for the production of both homologous and heterologous proteins
and challenges of using filamentous fungi for the production of heterologous proteins. We …

Production of recombinant proteins by filamentous fungi

OP Ward - Biotechnology advances, 2012 - Elsevier
protein production by filamentous fungi related to … produce single recombinant protein
products. An early recognized disadvantage of filamentous fungi as hosts of recombinant proteins

Recent studies of protein secretion by filamentous fungi

K Iwashita - Journal of Bioscience and Bioengineering, 2002 - Elsevier
… for the protein production using filamentous fungi (2,5-6). … expression and protein production
in filamentous fungi. This … of homologous and heterologous proteins both in submerged …

Strategies for improving heterologous protein production from filamentous fungi

DB Archer, DJ Jeenes, DA Mackenzie - Antonie Van Leeuwenhoek, 1994 - Springer
… A number of filamentous fungal species have been used as hosts for heterologous protein
production and an increasing range of proteins has been produced. Species of Aspergillus …

Heterologous protein expression in filamentous fungi

KMH Nevalainen, VSJ Te'o, PL Bergquist - Trends in biotechnology, 2005 - cell.com
… Yields of heterologous proteins produced in filamentous fungi The proteins of interest to be
produced in filamentous fungal systems fall roughly into two categories: industrial enzymes …

Regulation of secreted protein production by filamentous fungi: recent developments and perspectives

DA MacKenzie, DJ Jeenes, NJ Belshaw… - …, 1993 - microbiologyresearch.org
… heterologous proteins produced by filamentous fungi. … from filamentous fungi have been
identified as activator proteins … the regulatory proteins identified in filamentous fungi along with …

Making recombinant proteins in filamentous fungi-are we expecting too much?

H Nevalainen, R Peterson - Frontiers in microbiology, 2014 - frontiersin.org
… of fungally produced heterologous gene products is their mode of glycosylation; fungi lack
… protocols may result in new strategies to produce recombinant proteins in filamentous fungi. …

Protein expression and secretion by filamentous fungi

AA Sakekar, SR Gaikwad, NS Punekar - Journal of Biosciences, 2021 - Springer
… In this review, we examine different aspects of fungal platforms for protein production
including – the strain selection and development, morphology and culture conditions, designing …

[PDF][PDF] 9 Heterologous Protein Production by Filamentous Fungi

DJ Jeenes, DA Mackenzie, IN Roberts… - Biotechnology and …, 1991 - Taylor & Francis
… aspects of heterologous gene expression in filamentous fungi and the production of
heterologous proteins. The attractions of the filamentous fungi as hosts for heterologous protein