… Here we will use the general term ‘intrinsically disordered’ as a descriptor of proteins (and
protein regions) that fail to form specific 3-D structure under physiological conditions in vitro (…

… interventions and primary health care on intrinsic capacity (IC) and related biomarkers. …
of intrinsic capacity (IC), which comprises an individual's physical and mental capacities for …

… capacity of an individual (the intrinsic capacity) and the context of each individual's life (the
environment).3 Accordingly, healthy ageing depends upon intrinsic capacity… intrinsic capacity. …

… To assess whether the FinO domain itself is intrinsically selective or promiscuous, we
determine in vivo targets of Neisseria meningitidis, which consists of solely a FinO domain. UV-…

Frontiers | Intrinsic capacity rather than intervention exposure influences reversal to robustness
among prefrail community-dwelling older adults: A non-randomized controlled study of a …

… , and protein translation. In health, distinct T cells subtypes demonstrate differences in intrinsic
metabolic capacity … upon these cells, and further compound intrinsic impairments. These …

… ability, which comprises the interaction of environment and intrinsic capacity (IC; ie, the
composite of all the physical and mental capacities of an individual). The proposed key IC …

… Indeed, in mice that carry targeted Ab genes with low or high antigen-binding affinity to NP
hapten antigen, low- and high-affinity B cells have the same intrinsic capacity to respond to …

… In conclusion, JAK2 contributes to the intrinsic capacity of murine fetal liver hematopoietic
progenitor cells to respond to SCF. However, this requirement can be overcome in …

Many gene sequences in eukaryotic genomes encode entire proteins or large segments of
proteins that lack a well-structured three-dimensional fold. Disordered regions can be highly …