[HTML][HTML] … of acyl carnitines, pentose phosphate pathway and arginine and ornithine metabolism are associated with decline in intrinsic capacity in Chinese older adults

Y Pan, Y Li, JK Chhetri, P Liu, B Li, Z Liu… - Aging Clinical and …, 2024 - Springer
Intrinsic capacity is the combination of individual physical and mental … of the decline in
intrinsic capacity are still unclear. … Our results indicated that decline in intrinsic capacity had …

[HTML][HTML] Use of Intrinsic Capacity Domains as a Screening Tool in Public Health

LM Nascimento, TGC Cruz, JFL Silva, LP Silva… - International Journal of …, 2023 - mdpi.com
… One of the constructs used by this strategy is intrinsic capacity (IC), which is defined as the
composite of all the mental and physical capacities that a person can draw on over a lifetime [2…

B Cell–Intrinsic and–Extrinsic Regulation of Antibody Responses by PARP14, an Intracellular (ADP-Ribosyl) Transferase

SH Cho, A Raybuck, M Wei, J Erickson… - The Journal of …, 2013 - journals.aai.org
… We also found that in addition to a CD4 T cell–intrinsic capacity of this mART to promote
Th17 differentiation, enteric CD103 + DCs were reduced in Parp14 −/− mice, which may …

Low intrinsic running capacity is associated with reduced skeletal muscle substrate oxidation and lower mitochondrial content in white skeletal muscle

DA Rivas, SJ Lessard, M Saito… - American Journal …, 2011 - journals.physiology.org
… We show that a low intrinsic aerobic running capacity confers reduced insulin sensitivity in
… with high intrinsic running capacity. Furthermore, selection for high running capacity, in the …

Sustaining intrinsic growth capacity of adult neurons promotes spinal cord regeneration

S Neumann, K Skinner… - Proceedings of the …, 2005 - National Acad Sciences
… Taken together, these results demonstrated that the intrinsic growth capacity of the neurons,
… to sustain intrinsic growth capacity. We show that the regenerative capacity of injured axons …

Intrinsically disordered proteins in cellular signalling and regulation

PE Wright, HJ Dyson - Nature reviews Molecular cell biology, 2015 - nature.com
… We discuss how intrinsic disorder functions to enhance and propagate signalling. The
multiplicity of protein-interaction motifs in IDPs and their capacity for regulation through post-…

Enthalpy-entropy compensation and heat capacity changes for protein-ligand interactions: general thermodynamic models and data for the binding of nucleotides to …

MR Eftink, AC Anusiem, RL Biltonen - Biochemistry, 1983 - ACS Publications
… Also from the temperature derivative of A7/(app) one can obtain an expression for the
apparent heat capacity change(eq 4). Here we assume that there is no intrinsic heat capacity

Plasma Level of ATPase Inhibitory Factor 1 and Intrinsic Capacity in Community-Dwelling Older Adults: Prospective Data From the MAPT Study

JA da Silva, LO Martinez, Y Rolland… - The Journals of …, 2024 - academic.oup.com
… The concept suggests that functional ability, which depends on the interplay between both
environmental factors and intrinsic capacity (IC), is key to achieving overall well-being. IC, …

Intrinsic aerobic capacity sets a divide for aging and longevity

LG Koch, OJ Kemi, N Qi, SX Leng, P Bijma… - Circulation …, 2011 - Am Heart Assoc
… that divides widely for intrinsic (ie, untrained) aerobic exercise capacity, provide first
demonstration that an inherent aerobic capacity phenotype and cosegregated subphenotypes can …

[HTML][HTML] Patterns of participation restriction among older adults at risk of falls and relationship with intrinsic capacity: a latent cluster analysis

RA Merchant, YH Chan, I Aprahamian… - Frontiers in medicine, 2022 - frontiersin.org
… Our study showed that participants with a decline in at least three out of the six intrinsic
capacity domains had a probability of >80% of belonging to the low/moderate participation group. …