… is a powerful predictor of declines in intrinsic capacity, functional abilities, the onset of …
with measures of intrinsic capacity—a composite of all the physical and mental capacities of an …

… Figure 1 Protein transport through the ER (yellow) and activities of the UPR to couple the
ER protein-folding capacity with its protein-folding burden (purple). Abbreviations are ER, …

… This approach centres around the concept of raising intrinsic capacity (IC) and functional …
, IC comprises an individual’s physical and mental capacities at any given time.4 This novel …

Most proinflammatory actions of C-reactive protein (CRP) are only expressed following
dissociation of its native pentameric assembly into monomeric form (mCRP). However, little is …

… (HCR) intrinsic running capacity simultaneously present with … In conclusion, diminished
intrinsic exercise capacity impairs … with impairments in aerobic capacity and vascular endothelial …

… Citation 9 Together, our findings suggest that an enhanced capacity to clear misfolded
proteins may be an intrinsic characteristic of tumor cells, bolstering anti-oxidant defense to …

… Well-being can be achieved by improving functional ability, which depends on the interplay
between environmental factors and intrinsic capacity (IC). IC, which is a central aspect of this …

… proteins which operate as DAMPs to maintain and restore homeostasis. The unfolded protein
response is … expansion provides tremendous flexibility and capacity with regard to cargo, …

… people with priority conditions associated with declines in intrinsic capacity (IC). We aimed
to determine the clinical utility of the WHO ICOPE screening tool in a Chinese population. …

… by the intrinsic capacity (IC) … capacities”, which can be operationalized by five domains
including cognitive, locomotor, vitality, sensory (vision and hearing), and psychological capacities […