… The unfolded protein response (UPR) is a protective cellular response activated under …
The hepatic UPR is activated in several forms of liver disease including nonalcoholic fatty liver …

… homeostasis, the unfolded protein response, has been linked … the ER and the unfolded
protein response in the context of … upregulation of protein chaperones in the liver should improve …

… and imaging characteristic of nonalcoholic fatty liver disease is the accumulation of lipids…
protein response (UPR) which is classically viewed as an adaptive pathway to maintain protein …

… liver (NAFL) and nonalcoholic steatohepatitis (NASH) are associated with known triggers of
the unfolded protein response (… with liver histology. Methods: Messenger RNA (mRNA) and …

… -dimensional protein profile revealed major perturbations of unfolded protein response targets…
factors possibly contributing to liver steatosis or fibrosis under ER stress (eg, major urinary …

… the unfolded protein response (UPR), a signal transduction pathway that senses the fidelity
of protein folding in the ER lumen. The UPR transmits information about protein folding status …

… region/leucine zipper protein family … protein (DBP) and the CAAT/enhancer-binding proteins
(C/EBPs) for their importance in liver-specific gene expression and their role in liver function …

… The aim of the present study was to determine the changes in liver size, weight, and hepatic
protein synthesis in a large prospective clinical trial throughout acute hospitalization and up …

… take the synthesized proteins to their destination. The primary structure of the protein determines
both … Therefore, a key function of the ER is to ensure the fidelity of protein synthesis and …

… or food supplement to protect liver function. More relevant for a therapeutic setting was
our observation that NR administration was able to attenuate mitochondrial dysfunction and …